Publication Name	World Journal of Meta-Analysis
Manuscript ID	75551
Country	India

Category	Orthopedics
Manuscript Type	Meta-Analysis
Article Title	Is cellular therapy beneficial in management of rotator cuff tears? Meta-analysis of comparative clinical studies
Manuscript Source	Invited Manuscript
All Author List	Sathish Muthu, Cheruku Mogulesh, Vibhu Krishnan Viswanathan, Naveen Jeyaraman, Satvik N Pai, Madhan Jeyaraman and Manish Khanna
Funding Agency and Grant Number
Corresponding Author	Madhan Jeyaraman, MS, PhD, Assistant Professor, Research Associate, Department of Orthopaedics, Faculty of Medicine, Sri Lalithambigai Medical College and Hospital, Dr MGR Educational and Research Institute, Adayalampattu, Chennai 600095, Tamil Nadu , India. madhanjeyaraman@gmail.com
Key Words	Mesenchymal stromal cell; Bone-marrow derived mesenchymal stromal cell; Adipose-derived mesenchymal stromal cell; Rotator cuff tear; Cellular therapy; Meta-analysis
Core Tip	Biological augmentation of rotator cuff tears with mesenchymal stromal cell-based cellular therapy significantly reduces the pain severity and improves the functional outcome at 3 and 6 mo based on our critical review of clinical studies on the subject. Moreover, we noted enhanced radiological tendon healing, and mitigated retear rates at both short- and long-term follow-ups. We have also established the safety of using cellular therapy in patients presenting with rotator cuff tears.
Citation	Muthu S, Mogulesh C, Viswanathan VK, Jeyaraman N, Pai SN, Jeyaraman M, Khanna M. Is cellular therapy beneficial in management of rotator cuff tears? Meta-analysis of comparative clinical studies. World J Meta-Anal 2022; 10(3):162-176

Received	2022-02-04 07:43
Peer-Review Started	2022-02-04 07:45
To Make the First Decision
Return for Revision	2022-04-21 04:12
Revised	2022-05-02 15:45
Second Decision	2022-06-20 03:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-26 23:33
Articles in Press	2022-06-26 23:33
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-13 02:06
Typeset the Manuscript	2022-06-27 10:18

ISSN	2308-3840 (online)
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