Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	76162
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Wen Hao, Peng Li, Yong-Jun Wang, Ming Ji, Shu-Tian Zhang and Hai-Yun Shi
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Nova Program Z201100006820147 Beijing Municipal Administration of Hospitals’ Youth Program QML20180102
Corresponding Author	Hai-Yun Shi, MD, PhD, Associate Professor, National Clinical Research Centre for Digestive Disease, Beijing Digestive Disease Centre, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong’an Road, Xicheng Distric, Beijing 100050, China. shihaiyun1016@gmail.com
Key Words	Colorectal laterally spreading tumors; Subtype; Deep submucosal invasion; Endoscopic submucosal dissection
Core Tip	The incidence of laterally spreading tumors (LSTs) is continually increasing; however, the optimal strategy for resecting large colorectal LSTs is still under debate. Endoscopic submucosal dissection (ESD) and surgery each have their pros and cons. In this work, we demonstrated that it is highly recommend that non-granular pseudodepressed (NG-PD) and granular nodular mixed LSTs are removed through ESD, and given their substantial risk for deep submucosal invasion, surgery needs to be considered in NG-PD LSTs located in the rectosigmoid, especially those with positive non-lifting signs.
Citation	Hao XW, Li P, Wang YJ, Ji M, Zhang ST, Shi HY. Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors. World J Gastrointest Oncol 2022; 14(7): 1337-1347

Received	2022-03-15 09:25
Peer-Review Started	2022-03-15 09:25
To Make the First Decision
Return for Revision	2022-05-10 07:34
Revised	2022-05-24 14:23
Second Decision	2022-06-20 03:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-26 23:38
Articles in Press	2022-06-26 23:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-07-02 07:42

ISSN	1948-5204 (online)
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