Publication Name	World Journal of Clinical Cases
Manuscript ID	76221
Country	Croatia

Category	Infectious Diseases
Manuscript Type	Retrospective Study
Article Title	Field evaluation of COVID-19 rapid antigen test: Are rapid antigen tests less reliable among the elderly?
Manuscript Source	Invited Manuscript
All Author List	Irena Tabain, Djivo Cucevic, Nikola Skreb, Anna Mrzljak, Ivana Ferencak, Zeljka Hruskar, Anita Misic, Josipa Kuzle, Ana Marija Skoda, Hrvojka Jankovic and Tatjana Vilibic-Cavlek
Funding Agency and Grant Number
Corresponding Author	Anna Mrzljak, PhD, Adjunct Associate Professor, Department of Gastroenterology and Hepatology, University Clinical Hospital Zagreb, Kispaticeva 12, Zagreb 10000, Croatia. anna.mrzljak@gmail.com
Key Words	Coronavirus disease 2019; Severe acute respiratory syndrome coronavirus-2; Rapid antigen test; Real-time reverse transcription-polymerase chain reaction; Croatia
Core Tip	The global outbreak of coronavirus disease (COVID-19) leads to the development of SARS-CoV-2 rapid antigen-detection tests (RAT), as a fast and accurate diagnosis is crucial to curb the pandemic. Evaluated RAT demonstrated satisfactory performance with more reliable results in younger patients. The young age group was significantly less likely to be false negative, whereas the false negatives from the elderly group showed significantly lower Ct values. Therefore, RT-PCR remains a gold standard in the SARS-CoV-2 diagnosis.
Citation	Tabain I, Cucevic D, Skreb N, Mrzljak A, Ferencak I, Hruskar Z, Misic A, Kuzle J, Skoda AM, Jankovic H, Vilibic-Cavlek T. Field evaluation of coronavirus disease 2019 rapid antigen test: Are rapid antigen tests less reliable among the elderly? World J Clin Cases 2022; 10(19): 6456-6463

Received	2022-03-14 14:12
Peer-Review Started	2022-03-14 14:14
To Make the First Decision
Return for Revision	2022-03-24 03:46
Revised	2022-04-05 20:06
Second Decision	2022-05-16 03:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-17 02:24
Articles in Press	2022-05-17 02:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-11 04:48
Typeset the Manuscript	2022-06-15 10:53

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com