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6/26/2022 11:43:18 PM | Browse: 4 | Download: 18
Publication Name World Journal of Stem Cells
Manuscript ID 76469
Country/Territory Jordan
Category Nanoscience & Nanotechnology
Manuscript Type Minireviews
Article Title Prodigious therapeutic effects of combining mesenchymal stem cells with magnetic nanoparticles
Manuscript Source Invited Manuscript
All Author List Ejlal Abu-El-Rub, Ramada R Khasawneh and Fatimah Almahasneh
Funding Agency and Grant Number
Corresponding Author Ramada R Khasawneh, PhD, Associate Professor, Department of Anatomy and Histology, Yarmouk University, Shafiq Irshidat St, Irbid 21163, Jordan. ramada@yu.edu.jo
Key Words Mesenchymal stem cells; Magnetic nanoparticles; Tracking; Homing; Migration; Differentiation
Core Tip Mesenchymal stem cells (MSCs) have been thoroughly investigated in many disease models and they showed great therapeutic potential. Despite the confirmed therapeutic abilities of MSCs, many challenges still exist which hinder the transfer of these cells to the treatment guidelines. The incorporation of magnetic nanoparticles (MNPs) with MSCs has been reported to increase the therapeutic outcomes of MSCs by solving major challenges that impede their long–term regenerative effects. MNPs are able to improve the ability to track and deliver MSCs and to increase their migration, homing, survival and differentiation in vitro and in vivo. This may help increase the success rate of MSCs transplantation and thus increase the chance to include these cells in the treatment guidelines used in different clinical settings.
Citation Abu-El-Rub E, Khasawneh RR, Almahasneh F. Prodigious therapeutic effects of combining mesenchymal stem cells with magnetic nanoparticles. World J Stem Cells 2022; 14(7): 513-526
Received
2022-03-17 20:25
Peer-Review Started
2022-03-17 20:27
To Make the First Decision
Return for Revision
2022-04-25 23:08
Revised
2022-05-18 22:24
Second Decision
2022-06-20 03:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-26 23:43
Articles in Press
2022-06-26 23:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-07-22 00:10
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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