Publication Name	World Journal of Clinical Cases
Manuscript ID	80759
Country	Taiwan

Category	Endocrinology & Metabolism
Manuscript Type	Case Report
Article Title	Thyrotoxicosis in patients with a history of Graves’ disease after SARS-CoV-2 vaccination (adenovirus vector vaccine): Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Bo-Chang Yan and Rong-Rong Luo
Funding Agency and Grant Number
Corresponding Author	Rong-Rong Luo, MD, Doctor, Department of Internal Medicine, Far Eastern Memorial Hospital, No. 21 Section 2, Nanya S Road Banqiao Dist, New Taipei City 220, Taiwan. agelinro@gmail.com
Key Words	SARS-CoV-2 vaccine; Graves’ disease; Hyperthyroidism; Thyroid storm; Vaccine and thyroid disease; Case report
Core Tip	Thyroid storm is potentially life-threatening. If the diagnosis of thyroid storm is suspected, treatment should be initiated without delay. We report two cases with underlying Graves’ disease who experienced thyrotoxicosis and thyroid storm after receiving an adenovirus-vectored vaccine for coronavirus disease (COVID-19). Both had achieved disease remission before the vaccination. The pathophysiology of COVID-19 vaccine induced thyroid dysfunction still not well understood. However, early awareness of thyroid dysfunction following the vaccination could avoid the life-threatening events.
Citation	Yan BC, Luo RR. Thyrotoxicosis in patients with a history of Graves’ disease after SARS-CoV-2 vaccination (adenovirus vector vaccine): Two case reports. World J Clin Cases 2023; 11(5): 1122-1128

Received	2022-11-01 16:22
Peer-Review Started	2022-11-01 16:23
To Make the First Decision
Return for Revision	2022-12-19 07:33
Revised	2022-12-31 12:51
Second Decision	2023-01-18 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-01-19 02:50
Articles in Press	2023-01-19 02:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-02-03 07:56

ISSN	2307-8960 (online)
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