Publication Name	World Journal of Stem Cells
Manuscript ID	80788
Country	Poland

Category	Cell Biology
Manuscript Type	Review
Article Title	Mesenchymal stem cells in ischemic tissue regeneration
Manuscript Source	Invited Manuscript
All Author List	Renata Szydlak
Funding Agency and Grant Number
Corresponding Author	Renata Szydlak, PhD, Postdoc, Research Assistant Professor, Chair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, Kraków 31-034, Poland. renata.szydlak@doctoral.uj.edu.pl
Key Words	Ischemia; Mesenchymal stem cells; Regenerative medicine; Stem cell therapy; Clinical applications
Core Tip	Mesenchymal stem cell (MSC) transplantation is an innovative therapy with positive therapeutic effects for many ischemic diseases. Ischemia of an area is defined as insufficient blood supply to specific tissues and various organs or individual parts of the body. The leading cause of tissue ischemia is the narrowing or blockage of the lumen of an artery, most often due to the formation of atherosclerotic plaques, thrombus, or spasms of a specific artery. Here, the potential therapeutic mechanisms of MSCs in ischemic diseases were discussed, along with examples of preclinical and clinical studies.
Citation	Szydlak R. Mesenchymal stem cells in ischemic tissue regeneration. World J Stem Cells 2023; 15(2): 16-30

Received	2022-10-14 17:23
Peer-Review Started	2022-10-14 17:26
To Make the First Decision
Return for Revision	2022-11-05 04:09
Revised	2022-11-10 14:00
Second Decision	2022-12-12 03:43
Accepted by Journal Editor-in-Chief	2022-12-12 20:16
Accepted by Company Editor-in-Chief	2023-01-19 00:09
Articles in Press	2023-01-19 00:09
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-12-07 21:16
Typeset the Manuscript	2023-02-20 05:51

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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