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5/31/2023 7:52:52 AM | Browse: 30 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 85070
Country/Territory China
Category Hematology
Manuscript Type Case Report
Article Title Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Yun Sun, Xiao-Dong Yang, Jia Xu, Nuan-Nuan Xiu, Bo Ju and Xi-Chen Zhao
Funding Agency and Grant Number
Funding Agency Grant Number
The Specialized Scientific Research Fund Projects of The Medical Group of Qingdao University No: YLJT20201002
Corresponding Author Xi-Chen Zhao, MD, Chief Physician, Department of Hematology, The Central Hospital of Qingdao West Coast New Area, No 9, Huangpujiang Road, Qingdao 266555, Shandong, China. zhaoxichen2003@163.com
Key Words Case report; Myelodysplastic syndrome; Aplastc crisis; Atypical lymphocyte; Leukemic cell regression; CD56+ lymphocyte expansion; Disseminated tuberculosis
Core Tip In patients with myelodysplastic syndrome, bone marrow cellularity and myeloblasts usually increase with disease progression. An advanced myelodysplastic syndrome patient experienced an episode of aplastic crisis. During the aplastic crisis, leukemic cells regressed. The bone marrow was infiltrated with atypical lymphocytes that expressed high frequencies of cluster of differentiation (CD)3, CD5, CD8, CD16, CD56 and CD57. Antituberculosis treatment led to reversion of the aplastic crisis, disappearance of the atypical lymphocytes, increased marrow cellularity and 2 mo of hematological remission, suggesting that disseminated tuberculosis was responsible for the development of aplastic crisis, regression of leukemic cells and activation of CD56+ cells.
Citation Sun XY, Yang XD, Xu J, Xiu NN, Ju B, Zhao XC. Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature. World J Clin Cases 2023; 11(19): 4713-4722
Received
2023-04-10 13:42
Peer-Review Started
2023-04-10 13:44
To Make the First Decision
Return for Revision
2023-05-12 01:23
Revised
2023-05-22 04:44
Second Decision
2023-05-31 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-05-31 07:52
Articles in Press
2023-05-31 07:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-06-19 04:03
ISSN 2307-8960 (online)
Open Access
Copyright
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com