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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 89036
Country China
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title MicroRNA-298 determines the radio-resistance of colorectal cancer cells by directly targeting human dual-specificity tyrosine(Y)-regulated kinase 1A
Manuscript Source Unsolicited Manuscript
All Author List Mei-Zhu Shen, Yong Zhang, Fang Wu, Mei-Zhen Shen, Jun-Lin Liang, Xiao-Long Zhang, Xiao-Jian Liu, Xin-Shu Li and Ren-Sheng Wang
Funding Agency and Grant Number
Corresponding Author Ren-Sheng Wang, PhD, Doctor, Doctor, Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Qingxiu District, Nanning 530021, Guangxi Zhuang Autonomous Region, China. 13807806008@163.com
Key Words MicroRNA-298; Human dual-specificity tyrosine(Y)-regulated kinase 1A; Colorectal cancer; Radio-resistance; p53 binding protein 1
Core Tip Our findings indicate that microRNA-298 (miR-298) is upregulated in radio-resistant colorectal cancer (CRC) cells. Overexpression of miR-298 leads to decreased human dual-specificity tyrosine(Y)-regulated kinase 1A expression, ultimately enhancing the radio-resistance of CRC cells.
Citation Shen MZ, Zhang Y, Wu F, Shen MZ, Liang JL, Zhang XL, Liu XJ, Li XS, Wang RS. MicroRNA-298 determines the radio-resistance of colorectal cancer cells by directly targeting human dual-specificity tyrosine(Y)-regulated kinase 1A. World J Gastrointest Oncol 2024; 16(4): 1453-1464
Received
2023-12-05 06:52
Peer-Review Started
2023-12-05 06:52
To Make the First Decision
Return for Revision
2023-12-18 07:06
Revised
2023-12-31 17:55
Second Decision
2024-02-02 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-02-02 05:55
Articles in Press
2024-02-02 05:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-03-28 00:50
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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