Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	89834
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Xin Zhao, Yan Cui, Xin-Hong Li, Wen-Hong Yang, Shi-Xiang An, Jia-Xian Cui, Min-Yu Zhang, Jing-Kun Lu, Xuan Zhang, Xiu-Mei Wang, Li-Li Bao and Peng-Wei Zhao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82360329 Inner Mongolia Medical University General Project YKD2023MS047 Inner Mongolia Health Commission Science and Technology Plan Project 202201275
Corresponding Author	Peng-Wei Zhao, FEBG, FRS, Academic Research, School of Basic Medical Science, Inner Mongolia Medical University, No. 5 Xinhua Street, Hohhot 010059, Inner Mongolia Autonomous Region, China. pengwzhao@126.com
Key Words	Colon cancer; Human β-defensin-1; LncRNA; Mammalian target of rapamycin; Autophagy
Core Tip	Colorectal cancer has a low 5-year survival rate and high mortality. Human β-defensin-1 (hBD-1) is likely to play an integral function in the innate immune system, contributing to the recognition and destruction of cancer cells. Hence, we explored the effect of hBD-1 on colon cancer SW620 cells, which could be good for the development of therapy for colorectal cancer.
Citation	Zhao YX, Li XH, Cui Y, Yang WH, An SX, Cui JX, Zhang MY, Lu JK, Zhang X, Wang XM, Bao LL, Zhao PW. Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506. World J Gastrointest Oncol 2024; 16(4): 1465-1478

Received	2023-11-14 07:46
Peer-Review Started	2023-11-14 07:47
To Make the First Decision
Return for Revision	2024-01-05 09:20
Revised	2024-01-15 11:07
Second Decision	2024-02-18 01:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-18 05:06
Articles in Press	2024-02-18 05:06
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-02-14 10:34
Typeset the Manuscript	2024-03-08 00:49

ISSN	1948-5204 (online)
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