| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Phillip Gu, Shishir Dube, Norman Gellada, So Yung Choi, Susan Win, Yoo Jin Lee, Shaohong Yang, Talin Haritunians, Gil Y Melmed, Eric A Vasiliauskas, Niru Bonthala, Gaurav Syal, Andres J Yarur, David Ziring, Shervin Rabizadeh, Phillip Fleshner, Cindy Kallman, Suzanne Devkota, Stephan R Targan, Dalin Li and Dermot PB McGovern |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| American College of Gastroenterology |
ACG-CR-040-2022 |
| National Institute of Diabetes and Digestive and Kidney Diseases |
2299170 |
| Helmsley Charitable Trust |
2352240 |
|
| Corresponding Author |
Phillip Gu, MD, Assistant Professor, Doctor, Doctor, Department of Medicine, Cedars-Sinai Medical Center, 8730 Alden Dr
Suite E222, Los Angeles, CA 90048, United States. phillipgu12@gmail.com |
| Key Words |
Crohn’s disease; Surgery; Visceral adipose tissue; Mesenteric adipose tissue; Creeping fat; Computed tomography |
| Core Tip |
Risk stratification for post-operative recurrence of Crohn’s disease (CD) remains a clinical challenge. We evaluated the prognostic value of pre-operative radiographic mesenteric parameters for post-operative recurrence of CD. Of the parameters evaluated, lower visceral adipose tissue radiodensity was independently associated with post-operative recurrence. Visceral adipose tissue radiodensity may be a novel imaging prognostic marker to help risk stratify for post-operative recurrence of CD during pre-operative work up. |
| Citation |
Gu P, Dube S, Gellada N, Choi SY, Win S, Lee YJ, Yang S, Haritunians T, Melmed GY, Vasiliauskas EA, Bonthala N, Syal G, Yarur AJ, Ziring D, Rabizadeh S, Fleshner P, Kallman C, Devkota S, Targan SR, Li D, McGovern DPB. Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease. World J Gastrointest Surg 2024; 16(3): 740-750 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
