Publication Name	World Journal of Hepatology
Manuscript ID	90669
Country	United Kingdom

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Palliative long-term abdominal drains vs large volume paracenteses for the management of refractory ascites in end-stage liver disease
Manuscript Source	Invited Manuscript
All Author List	Senamjit Kaur, Rodrigo V Motta, Bryony Chapman, Victoria Wharton, Jane D Collier and Francesca Saffioti
Funding Agency and Grant Number
Corresponding Author	Francesca Saffioti, MD, PhD, Consultant Physician-Scientist, Researcher, Oxford Liver Unit, Department of Gastroenterology and Hepatology, Oxford University Hospitals NHS Foundation Trust, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. francesca.saffioti@nhs.net
Key Words	Decompensated liver cirrhosis; Indwelling abdominal catheter; Rocket drain; Palliative care; Safety; Quality of life
Core Tip	The standard treatment of refractory ascites in palliated patients with end-stage liver disease is repeated large volume paracentesis (LVP) with albumin infusion. This study focuses on real-world data comparing the effectiveness and safety of long-term abdominal drains (LTAD) in comparison with LVP. The incidence of acute kidney injury, ascites and drain-related hospital admissions was lower in the LTAD group. There was no difference in the overall survival between the two groups, but time to acute kidney injury, first ascites/drain-related hospital admission and drain-related complications were shorter in the LTAD group.
Citation	Kaur S, Motta RV, Chapman B, Wharton V, Collier JD, Saffioti F. Palliative long-term abdominal drains vs large volume paracenteses for the management of refractory ascites in end-stage liver disease. World J Hepatol 2024; 16 (3): 428-438

Received	2023-12-10 19:07
Peer-Review Started	2023-12-10 19:07
To Make the First Decision
Return for Revision	2023-12-28 22:04
Revised	2024-01-25 01:07
Second Decision	2024-02-29 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-29 06:51
Articles in Press	2024-02-29 06:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-11 02:32

ISSN	1948-5182 (online)
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