BPG is committed to discovery and dissemination of knowledge
Articles in Press
4/11/2024 7:42:32 AM | Browse: 170 | Download: 0
Publication Name World Journal of Experimental Medicine
Manuscript ID 91519
Country Argentina
Category Pharmacology & Pharmacy
Manuscript Type Minireviews
Article Title Sodium-glucose cotransporter-2 inhibitors protect tissues via cellular and mitochondrial pathways: Experimental and clinical evidence
Manuscript Source Invited Manuscript
All Author List Raúl Lelio Sanz, Sebastián García Menéndez, Felipe Inserra, Leon Ferder and Walter Manucha
Funding Agency and Grant Number
Corresponding Author Walter Manucha, PhD, Adjunct Professor, Department of Pathology, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Campus Universitario Uncuyo, Mendoza 5500, Argentina. wmanucha@fcm.uncu.edu.ar
Key Words Sodium-glucose cotransporter-2 inhibitors; Cardiovascular diseases; Sirtuins; Oxidative stress; Inflammation; Mitochondrial dysfunction
Core Tip Sodium-glucose cotransporter-2 inhibitors, diabetes drugs, unlock tissue protection via diverse pathways. They boost mitochondrial efficiency, curb oxidative stress and inflammation, and enhance autophagy. Clinical trials show cardiovascular benefits, suggesting immense potential beyond diabetes and even towards anti-aging therapy.
Citation

Sanz RL, García Menéndez S, Inserra F, Ferder L, Manucha W. Sodium-glucose cotransporter-2 inhibitors protect tissues via cellular and mitochondrial pathways: Experimental and clinical evidence. World J Exp Med 2024; 14(2): 91519

Received
2023-12-29 20:16
Peer-Review Started
2023-12-29 20:16
First Decision by Editorial Office Director
2024-01-21 05:28
Return for Revision
2024-01-21 05:28
Revised
2024-02-07 14:04
Publication Fee Transferred
Second Decision by Editor
2024-04-11 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-04-11 07:42
Articles in Press
2024-04-11 07:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-06-11 02:23
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com