Publication Name	World Journal of Experimental Medicine
Manuscript ID	91519
Country	Argentina

Category	Pharmacology & Pharmacy
Manuscript Type	Minireviews
Article Title	Sodium-glucose cotransporter-2 inhibitors protect tissues via cellular and mitochondrial pathways: Experimental and clinical evidence
Manuscript Source	Invited Manuscript
All Author List	Raúl Lelio Sanz, Sebastián García Menéndez, Felipe Inserra, Leon Ferder and Walter Manucha
Funding Agency and Grant Number
Corresponding Author	Walter Manucha, PhD, Adjunct Professor, Department of Pathology, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Campus Universitario Uncuyo, Mendoza 5500, Argentina. wmanucha@fcm.uncu.edu.ar
Key Words	Sodium-glucose cotransporter-2 inhibitors; Cardiovascular diseases; Sirtuins; Oxidative stress; Inflammation; Mitochondrial dysfunction
Core Tip	Sodium-glucose cotransporter-2 inhibitors, diabetes drugs, unlock tissue protection via diverse pathways. They boost mitochondrial efficiency, curb oxidative stress and inflammation, and enhance autophagy. Clinical trials show cardiovascular benefits, suggesting immense potential beyond diabetes and even towards anti-aging therapy.
Citation	<p>Sanz RL, García Menéndez S, Inserra F, Ferder L, Manucha W. Sodium-glucose cotransporter-2 inhibitors protect tissues via cellular and mitochondrial pathways: Experimental and clinical evidence. <i>World J Exp Med</i> 2024; 14(2): 91519</p>

Received	2023-12-29 20:16
Peer-Review Started	2023-12-29 20:16
To Make the First Decision
Return for Revision	2024-01-21 05:28
Revised	2024-02-07 14:04
Second Decision	2024-04-11 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-11 07:42
Articles in Press	2024-04-11 07:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-11 02:23

ISSN	2220-315x (online)
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