Publication Name	World Journal of Clinical Oncology
Manuscript ID	91707
Country	China

Category	Cell Biology
Manuscript Type	Editorial
Article Title	New targets for cancer promotion and therapy in gliomas: Scinderin
Manuscript Source	Invited Manuscript
All Author List	Xi Wang and Lian-Xiang Luo
Funding Agency and Grant Number
Corresponding Author	Lian-Xiang Luo, PhD, Adjunct Associate Professor, The Marine Biomedical Research Institute, Guangdong Medical University, No. 2 Wenming East Road, Zhanjiang 524000, Guangdong Province, China. luolianxiang321@gdmu.edu.cn
Key Words	Glioma; Scinderin; Actin cytoskeleton; RhoA/FAK signaling; 1p/19q co-deletion
Core Tip	The role of scinderin (SCIN) in cancer progression has been studied, but its role in glioma remains unknown. Lin et al found that the expression level of SCIN mRNA was positively correlated with the tumor grade of glioma. SCIN affected cytoskeletal remodeling and inhibited lamellipodia formation through RhoA/FAK signaling pathway, thereby facilitating the migration and invasion of glioma cells.
Citation	<p>Wang X, Luo LX. New targets for cancer promotion and therapy in gliomas: Scinderin. <i>World J Clin Oncol</i> 2024; 15(6): 687-690</p>

Received	2024-01-03 01:26
Peer-Review Started	2024-01-03 01:26
To Make the First Decision
Return for Revision	2024-04-10 05:57
Revised	2024-04-27 16:23
Second Decision	2024-05-20 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-20 08:23
Articles in Press	2024-05-20 08:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-29 08:25

ISSN	2218-4333 (online)
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