Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	92098
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Bang Liu, Zhao-Xiong Zhang, Xin-Yang Nie, Wei-Lin Sun, Yong-Jia Yan and Wei-Hua Fu
Funding Agency and Grant Number	Funding Agency Grant Number Health Science and Technology Project of Tianjin Health Commission ZC20190 Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-005A Tianjin Medical University Clinical Research Fund 22ZYYLCCG04
Corresponding Author	Wei-Hua Fu, MD, PhD, Professor, Surgeon, Teacher, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, No. 154 Anshan Road, Tianjin 300052, China. tjmughgs_fwh@163.com
Key Words	T4N0M0 colon cancer; Prognosis; Multivariate analysis; Nomogram; Colon cancer
Core Tip	Paradoxically, patients with T4N0M0 (stage II, no lymph node metastasis) colon cancer have a worse prognosis than those with T2N1-2M0 (stage III). However, no previous report has addressed this issue. A total of 200 patients underwent radical surgery with pTNM “T4N0M0” were enrolled in this study. The clinical data and outcomes of the 200 patients were analyzed. We confirmed enterostomy, T stage, right hemicolon, irregular review, carbohydrate antigen 199 were independent risk factors of overall survival by using multivariate analysis. A nomogram model based on these factors was established to predict the prognosis of patients with T4N0M0 colon cancer.
Citation	Liu B, Zhang ZX, Nie XY, Sun WL, Yan YJ, Fu WH. Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study. World J Gastrointest Oncol 2024; 16(5): 1869-1877

Received	2024-01-15 07:15
Peer-Review Started	2024-01-15 07:15
To Make the First Decision
Return for Revision	2024-02-05 20:31
Revised	2024-02-14 15:19
Second Decision	2024-03-28 01:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-28 05:00
Articles in Press	2024-03-28 05:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-22 04:33

ISSN	1948-5204 (online)
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