Publication Name	World Journal of Gastroenterology
Manuscript ID	93857
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Advances in understanding and managing celiac disease: Pathophysiology, treatment strategies
Manuscript Source	Invited Manuscript
All Author List	Hao-Jie Ge and Xu-Lin Chen
Funding Agency and Grant Number
Corresponding Author	Xu-Lin Chen, MD, Director, Director, Doctor, Doctor, Department of Burns, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui Province, China. okcxl@126.com
Key Words	Celiac disease; Gluten-free diet; Pathology; Human leukocyte antigen; Immunotherapy; Treatment; Aspergillus niger prolyl endoprotease
Core Tip	This editorial provides a comprehensive review of the pathophysiological mechanisms underlying celiac disease and explores emerging therapeutic strategies, including the potential role of Aspergillus niger-derived prolyl endopeptidase. The discussion emphasizes the need for new treatments that address the multifaceted nature of the disease, aiming to improve patient quality of life beyond the limitations of a strict gluten-free diet.
Citation	<p>Ge HJ, Chen XL. Advances in understanding and managing celiac disease: Pathophysiology, treatment strategies. <i>World J Gastroenterol</i> 2024; 30(35): 3932-3941</p>

Received	2024-03-06 16:54
Peer-Review Started	2024-03-06 16:54
To Make the First Decision
Return for Revision	2024-08-01 22:12
Revised	2024-08-12 20:43
Second Decision	2024-08-26 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-26 06:16
Articles in Press	2024-08-26 06:16
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-08-28 02:40
Typeset the Manuscript	2024-08-29 11:15

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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