Publication Name	World Journal of Critical Care Medicine
Manuscript ID	98419
Country	United Kingdom

Category	Critical Care Medicine
Manuscript Type	Editorial
Article Title	Diabetic foot attack: Managing severe sepsis in the diabetic patient
Manuscript Source	Invited Manuscript
All Author List	Kisshan Raj Balakrishnan, Dharshanan Raj Selva Raj, Sabyasachi Ghosh and Gregory AJ Robertson
Funding Agency and Grant Number
Corresponding Author	Kisshan Raj Balakrishnan, Department of Trauma and Orthopaedics, Wrexham Maelor Hospital, Croesnewydd Road, Wrexham LL13 7TD, United Kingdom. kisshan.raj1108@gmail.com
Key Words	Diabetic foot attack; Diabetic foot infection; Diabetes mellitus; Sepsis; Systemic sepsis
Core Tip	Diabetic foot attack (DFA) represents the most severe presentation of diabetic foot disease, with typical and atypical forms that require distinct management strategies. A typical DFA results from a severe infection of the foot, propagated by the associated diabetic pathophysiology, leading to rapid spread of infection, tissue necrosis and potential systemic sepsis. An atypical DFA arises from either ischemia or Charcot arthropathy. Effective management of DFA necessitates early diagnosis, aggressive treatment of infections, and a multidisciplinary approach involving critical care, surgical intervention, and diabetes management teams. Current treatment practices are informed by guidelines for diabetic foot infections, but there is a critical need for dedicated research to develop standardized protocols for DFA management. This review highlights the urgent need for comprehensive care and research to optimize outcomes for patients experiencing DFA.
Citation	<p>Balakrishnan KR, Selva Raj DR, Ghosh S, Robertson GA. Diabetic foot attack: Managing severe sepsis in the diabetic patient. <i>World J Crit Care Med</i> 2025; 14(1): 98419</p>

Received	2024-08-28 06:53
Peer-Review Started	2024-06-25 21:17
To Make the First Decision
Return for Revision	2024-09-23 12:05
Revised	2024-10-23 17:15
Second Decision	2024-11-15 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-15 08:12
Articles in Press	2024-11-15 08:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-04 02:19

ISSN	2220-3141(online)
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