Publication Name	World Journal of Psychiatry
Manuscript ID	98436
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Meta-Analysis
Article Title	Potential clinical benefits of probiotics, prebiotics, synbiotics, and postbiotics for depression via the microbiota-gut-brain axis
Manuscript Source	Unsolicited Manuscript
All Author List	Ling-Yi Dai, Ru-Ru Chen, Hao-Ran Chen, Jia-Hui Yin, Zhen-Xing Huang, Bo-Wen Yin and Xing-Yan Liu
Funding Agency and Grant Number
Corresponding Author	Xing-Yan Liu, BMed, Professor, Department of General Psychiatry, Wenzhou Seventh People's Hospital, No. 158, XuqianRoad, Panqiao Street, Ouhai District, Wenzhou 325000, Zhejiang Province, China. 13645771028@163.com
Key Words	Probiotics; Prebiotics; Synbiotics; Postbiotics; Depression; Gut microbiota
Core Tip	The present study evaluated the effect of probiotics, prebiotics, synbiotics, and postbiotics (PPSP)-based treatment on depressive symptoms by analyzing data from 14 studies comprising 906 participants. Results indicated that PPSP could significantly improve symptoms in patients with depression compared with placebo, while subgroup analysis confirmed the apparent effects of probiotics and synbiotics in improving depressive symptoms. Larger randomized controlled trials, nevertheless, are required to further explore the benefits of PPSP in treating depression.
Citation	<p>Dai LY, Chen RR, Chen HR, Yin JH, Huang ZX, Yin BW, Liu XY. Potential clinical benefits of probiotics, prebiotics, synbiotics, and postbiotics for depression via the microbiota-gut-brain axis. <i>World J Psychiatry</i> 2025; 15(5): 98436</p>

Received	2024-08-20 08:33
Peer-Review Started	2024-08-20 08:33
To Make the First Decision
Return for Revision	2025-01-16 12:41
Revised	2025-02-06 03:18
Second Decision	2025-04-07 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-07 07:31
Articles in Press	2025-04-07 07:31
Publication Fee Transferred	2025-02-26 03:44
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-17 02:49

ISSN	2220-3206 (online)
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