| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Diagnostic Accuracy and Cost-Effectiveness of the CAR-OLT Score in Predicting Cardiac Risk for Liver Transplantation
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Biolato, Luca Miele, Alfonso W Avolio, Giuseppe Marrone, Antonio Liguori, Francesco Galati, Anna Petti, Lidia Tomasello, Daniela Pedicino, Antonella Lombardo, Alessia D'Aiello, Maurizio Pompili, Salvatore Agnes, Antonio Gasbarrini and Antonio Grieco |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Marco Biolato, MD, PhD, Department of Medical and Surgical Sciences, Centro Malattie Apparato Digerente (CEMAD), Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricerca e Cura a Carattere Scientifico, Largo A. Gemelli 8, Rome 00168, Italy. marco.biolato@policlinicogemelli.it |
| Key Words |
Transplantation; Coronary artery disease; Pharmacoeconomic; Listing; Major adverse cardiovascular events |
| Core Tip |
The burden of cardiovascular risk factors and coronary artery disease among liver transplant (LT) candidates is increasing, but the optimal diagnostic cardiac work-up remains debated. The CAR-OLT score (available at www.carolt.us), based on twelve pre-transplant characteristics, predicts major adverse cardiovascular events (MACE) one year after LT. In our population, a CAR-OLT score cut-off of ≤23 identifies low-risk patients who could directly proceed to LT listing without additional diagnostic tests. This approach could have avoided 87 stress tests and 13 coronary angiographies, saving an estimated €574.70 per patient for the Italian National Health System. |
| Citation |
<p>Biolato M, Miele L, Avolio AW, Marrone G, Liguori A, Galati F, Petti A, Tomasello L, Pedicino D, Lombardo A, D'Aiello A, Pompili M, Agnes S, Gasbarrini A, Grieco A. Diagnostic Accuracy and Cost-Effectiveness of the CAR-OLT Score in Predicting Cardiac Risk for Liver Transplantation. <i>World J Transplant</i> 2025; 15(2): 99208</p> |
