Publication Name	World Journal of Orthopedics
Manuscript ID	32965
Country	India

Category	Orthopedics
Manuscript Type	Diagnostic Advances
Article Title	Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts
Manuscript Source	Invited Manuscript
All Author List	Kanhaiyalal Agrawal, Sujit Kumar Tripathy, Ramesh Kumar Sen, S Santhosh and Anish Bhattacharya
Funding Agency and Grant Number
Corresponding Author	Sujit Kumar Tripathy, Department of Orthopaedics, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar 751019, India. sujitortho@aiimsbhubaneswar.edu.in
Key Words	Osteonecrosis; Avascular necrosis; Bone scan; Magnetic resonance imaging; Photon emission computed tomography scan; Single photon emission computed tomography/computed tomography
Core Tip	Early diagnosis and treatment remains the key to hip preservation in osteonecrosis (ON). Till date magnetic resonance imaging (MRI) is considered as the gold standard diagnostic modality for ON. However with the improvement in nuclear imaging technique, the disease can be diagnosed even at a very early stage. Available literature suggests that single photon emission computed tomography/computed tomography (CT) bone scan and 18F-fluoride photon emission computed tomography/CT have similar or better results in comparison to MRI in ON of the femoral head. They also provide both morphological and metabolic information in the disease part and hence can indicate whether the disease is active or healed.
Citation	Agrawal K, Tripathy SK, Sen RK, Santhosh S, Bhattacharya A. Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts. World J Orthop 2017; 8(10): 747-753

Received	2017-02-01 12:51
Peer-Review Started	2017-02-07 11:06
To Make the First Decision	2017-07-10 00:37
Return for Revision	2017-07-10 08:15
Revised	2017-08-02 17:01
Second Decision	2017-08-10 03:38
Accepted by Journal Editor-in-Chief	2017-08-10 21:36
Accepted by Company Editor-in-Chief	2017-08-16 02:31
Articles in Press	2017-08-16 02:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-21 03:02

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com