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9/13/2017 7:37:40 PM | Browse: 23 | Download: 54
Publication Name World Journal of Clinical Cases
Manuscript ID 34766
Country of Manuscript Source Japan
Specialty Pathology
Manuscript Type Case Report
Article Title Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway
Manuscript Source Unsolicited Manuscript
All Author List Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Yasuko Fujita, Mitsumasa Osakabe, Keisuke Koeda, Takashi Kosaka, Shunichi Yanai, Kazuyuki Ishida, Akira Sasaki, Takayuki Matsumoto and Tamotsu Sugai
Funding Agency and Grant Number
Correspondence To Tamotsu Sugai, MD, Professor, Department of Molecular Diagnostic Pathology, Iwate Medical University, 19-1, Morioka 020-8505, Japan. tsugai@iwate-med.ac.jp
Keywords Stomach; Neuroendocrine tumor G2; Neuroendocrine tumor G3; Neuroendocrine carcinoma
Core Tip Gastric neuroendocrine carcninoma (NEC) is typically generated by dedifferentiation of adenocarcinoma cells to endocrine cells. However, we experienced a case of gastric NEC possibly generated from the neuroendocrine tumor (NET) component. The present case demonstrated an unconventional carcinogenic pathway in neuroendocrine tumorigenesis. In addition, we analyzed allelic imbalance (AI) in NET and NEC components and provided important insights into neuroendocrine carcinogenesis.
Citation Uesugi N, Sugimoto R, Eizuka M, Fujita Y, Osakabe M, Koeda K, Kosaka T, Yanai S, Ishida K, Sasaki A, Matsumoto T, Sugai T. Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. World J Clin Cases 2017; In press
Received
2017-06-01 01:23
Peer-Review Started
2017-06-03 06:46
To Make the First Decision
2017-06-27 01:44
Return for Revision
2017-06-28 11:10
Revised
2017-07-13 05:54
Second Decision
2017-08-30 04:34
Accepted by Journal Editor-in-Chief
2017-08-30 05:29
Accepted by Company Editor-in-Chief
2017-09-13 19:37
Articles in Press
2017-09-13 19:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Ze-Mao Gong
Reviewer Code 03002224, 00050849, and 01191922
Editorial Director Jin-Lei Wang
Journal Chief Editor Shuhei Yoshida
Company Chief Editor Na Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Revised Manuscript 34766-Review.docx
Peer-review Report 34766-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 34766-Journal editor-in-chief review report.pdf
Answering Reviewers 34766-Answering reviewers.pdf
Scientific Misconduct Check 34766-Scientific misconduct check.pdf
Scientific Editor Work List 34766-Scientific editor work list.pdf
Audio 34766-Audio core tip.mp3
Conflict-of-Interest Statement 34766-Conflict-of-interest statement.pdf
Copyright Assignment 34766-Copyright assignment.pdf
Informed Consent Statement 34766-Informed consent statement.pdf
Non-Native Speakers of English 34766-Language certificate.pdf