Publication Name	World Journal of Gastroenterology
Manuscript ID	35301
Country	United Kingdom

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Fatal gastrointestinal histoplasmosis 15 years after orthotopic liver transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Nikita Agrawal, David EJ Jones, Jessica K Dyson, Tim Hoare, Sharon A Melmore, Stephanie Needham and Nick P Thompson
Funding Agency and Grant Number
Corresponding Author	Nick P Thompson, MD, Department of Gastroenterology, Freeman Hospital, High Heaton, High Heaton, Newcastle upon Tyne NE7 YDN, United Kingdom. nick.thompson@nuth.nhs.uk
Key Words	Histoplasmosis; Orthotopic liver transplant; Primary biliary cholangitis; Primary biliary cholangitis
Core Tip	Histoplasmosis is an endemic fungal infection in many parts of the world; the majority of hosts remain asymptomatic. Clinical manifestations are most commonly pulmonary. We present an unusual case of Histoplasmosis occurring in a patient who was living in a non-endemic region, developed the disease after 15 years of immunosuppression following an orthotopic liver transplant, she presented with no pulmonary symptoms but rather luminal GI and systemic symptoms. This highlights the importance of considering Histoplasmosis within the differential of immunosuppressed patients with a past relevant travel history who present with diarrhea, weight loss, abdominal pain and granulomatous colitis.
Citation	Agrawal N, Jones DEJ, Dyson JK, Hoare T, Melmore SA, Needham S, Thompson NP. Fatal gastrointestinal histoplasmosis 15 years after orthotopic liver transplantation. World J Gastroenterol 2017; 23(43): 7807-7812

Received	2017-07-20 00:44
Peer-Review Started	2017-07-20 08:25
To Make the First Decision	2017-08-10 00:34
Return for Revision	2017-08-10 06:32
Revised	2017-09-28 20:42
Second Decision	2017-10-11 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-10-17 20:14
Articles in Press	2017-10-17 20:14
Publication Fee Transferred	2017-11-03 15:43
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-11-14 00:54

ISSN	1007-9327 (print) and 2219-2840 (online)
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