Publication Name	World Journal of Gastroenterology
Manuscript ID	36612
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Hepatitis C virus core protein-induced miR-93-5p inhibits IFN signaling pathway through targeting IFNAR1
Manuscript Source	Unsolicited Manuscript
All Author List	Chang-Long He, Ming Liu, Zhao-Xia Tan, Ya-jun Hu, Qiao-Yue Zhang, Xue-Mei Kuang, Wei-Long Kong and Qing Mao
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of China 81371849 the TMMU Key Project for Clinical Research 2012XLC05
Corresponding Author	Qing Mao, MD, PhD, Doctor, Doctor, Institute of Infectious Diseases, Southwest Hospital, Army Medical University (Former: The Third Military Medical University), Gaotanyan street, Shapingba distinct, Chongqing 400037, China. qingmao@tmmu.edu.cn
Key Words	IFN signaling pathway; Interferon receptor 1; miR-93-5p; Hepatitis C virus
Core Tip	Hepatitis C virus-1b core protein increases miR-93-5p expression and induces inactivation of the IFN signaling pathway. miR-93-5p expression is involved in pegylated interferon-α resistance and directly targets interferon receptor 1 (IFNAR1). miR-93-5p-IFNAR1 axis regulates STAT1 phosphorylation.
Citation	He CL, Liu M, Tan ZX, Hu YJ, Zhang QY, Kuang XM, Kong WL, Mao Q. Hepatitis C virus core protein-induced miR-93-5p up-regulation inhibits interferon signaling pathway by targeting IFNAR1. World J Gastroenterol 2018; 24(2): 226-236

Received	2017-10-27 02:08
Peer-Review Started	2017-10-27 06:08
To Make the First Decision	2017-11-22 01:10
Return for Revision	2017-11-27 10:47
Revised	2017-12-05 08:29
Second Decision	2017-12-12 07:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-12-12 19:51
Articles in Press	2017-12-12 19:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-12-16 13:22
Typeset the Manuscript	2018-01-05 07:03

ISSN	1007-9327 (print) and 2219-2840 (online)
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