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Publication Name World Journal of Gastroenterology
Manuscript ID 39909
Country/Territory Italy
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Locoregional therapy response in patients with hepatocellular cancer waiting for liver transplantation: Only selection or biological effect?
Manuscript Source Invited Manuscript
All Author List Quirino Lai, Michele Di Martino, Pierleone Lucatelli and Gianluca Mennini
Funding Agency and Grant Number
Corresponding Author Quirino Lai, MD, PhD, Academic Fellow, Academic Research, Assistant Lecturer, Doctor, Senior Lecturer, Hepato-bilio-pancreatic and Liver Transplant Unit, Department of Surgery, Sapienza University of Rome, Umberto I Policlinic of Rome, Viale del Policlinico 155, Rome 00161, Italy. lai.quirino@libero.it
Key Words Allocation; Recurrence; Trans-arterial chemo-embolization; Radiofrequency ablation; Model for end-stage liver disease
Core Tip The role of locoregional treatments in the setting of hepatocellular cancer and liver transplantation is controversial. On one side, neoadjuvant approaches should consent a selection of tumor aggressiveness. On the other side, a real survival improvement thanks to the tumor ablation should be achieved. Recent evidences report an effective beneficial role of locoregional strategies in terms of survival and recurrence. However, several biases must be taken into account in these studies, due to the heterogeneous characteristics of treated vs untreated subjects. Further studies are need with the intent to clarify this important topic.
Citation Lai Q, Di Martino M, Lucatelli P, Mennini G. Locoregional therapy response in patients with hepatocellular cancer waiting for liver transplantation: Only selection or biological effect? World J Gastroenterol 2018; 24(31): 3469-3471
Received
2018-05-18 09:38
Peer-Review Started
2018-05-19 13:19
To Make the First Decision
2018-05-30 01:32
Return for Revision
2018-06-04 08:53
Revised
2018-06-29 08:45
Second Decision
2018-07-13 09:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-07-16 01:46
Articles in Press
2018-07-16 01:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-08-16 06:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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