Publication Name	World Journal of Clinical Cases
Manuscript ID	40627
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Case Report
Article Title	CNKSR2 mutation causes the X-linked epilepsy-aphasia syndrome: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Sun, Yi-Dan Liu, Zhi-Feng Xu, Qing-Xia Kong and Yan-Ling Wang
Funding Agency and Grant Number	Funding Agency Grant Number Jining Medical University JYP201740
Corresponding Author	Qing-Xia Kong, MD, PhD, Chief Doctor, Department of Neurology, Affiliated Hospital of Jining Medical University, Guhuai Road No. 89, Jining 272000, Shandong Province, China. kxdqy8@sohu.com
Key Words	Epilepsy; Language impairment; Mental retardation; De novo mutation of CNKSR2; X-linked epilepsy-aphasia syndrome
Core Tip	Patient with epileptic seizures and progressive language impairment. Genetic testing revealed a de novo mutation of the CNKSR2 gene in the child and was not detected in the parents. Therefore, the gene may lead to X-linked epilepsy aphasia syndrome.
Citation	Sun Y, Liu YD, Xu ZF, Kong QX, Wang YL. CNKSR2 mutation causes the X-linked epilepsy-aphasia syndrome: A case report and review of literature. World J Clin Cases 2018; 6(12): 570-576

Received	2018-07-02 00:39
Peer-Review Started	2018-07-02 01:55
To Make the First Decision	2018-08-01 03:08
Return for Revision	2018-08-07 01:57
Revised	2018-08-21 15:09
Second Decision	2018-08-28 10:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-08-28 14:32
Articles in Press	2018-08-28 14:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-18 07:01

ISSN	2307-8960 (online)
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