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Publication Name World Journal of Radiology
Manuscript ID 41399
Country of Manuscript Source Thailand
Specialty Radiology, Nuclear Medicine and Medical Imaging
Manuscript Type Basic Study
Article Title Effects of muscle fiber orientation to main magnetic field on muscle metabolite profiles for magnetic resonance spectroscopy acquisition
Manuscript Source Unsolicited Manuscript
All Author List Duanghathai Pasanta, Tipparat Kongseha and Suchart Kothan
Funding Agency and Grant Number
Funding Agency Grant Number
Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Thailand
Correspondence To Suchart Kothan, PhD, Associate Professor, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 110 Intawaroros Rd., Sripoom, Chiang Mai 50200, Thailand. suchart.kothan@cmu.ac.th
Keywords Proton magnetic resonance spectroscopy; Metabolite; Muscle fiber orientation; Intramyocellular lipids; Extramyocellular lipids; Magnetic susceptibility
Core Tip Proton magnetic resonance spectroscopy (1H MRS) is a technique that is widely used for intramyocellular lipids and extramyocellular lipids quantification in muscles, as evidenced in various studies. However, different muscle positions can potentially lead to inconsistency in metabolite quantification and can also impede interpretation of data, which can lead to misinformation. This study reveals that the muscle orientation at 0°, 30°, 60°, and 90° to the main magnetic field significantly affects the metabolite profile and quantification. The metabolite profile changes due to the muscle fiber orientation demonstrate that the positioning potentially causes inaccuracy in 1H-MRS spectrum analysis.
Citation Pasanta D, Kongseha T, Kothan S. Effects of muscle fiber orientation to main magnetic field on muscle metabolite profiles for magnetic resonance spectroscopy acquisition. World J Radiol 2019; In press
Received
2018-08-06 06:30
Peer-Review Started
2018-08-07 01:00
To Make the First Decision
2018-10-17 01:38
Return for Revision
2018-10-22 01:46
Revised
2018-11-14 16:22
Second Decision
2019-01-08 11:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-10 00:22
Articles in Press
2019-01-10 00:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8470 (online)
Open Access
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Ying Dou
Reviewer Code 00607640, 02566952, and 02577402
Editorial Director Jin-Lei Wang
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Revised Manuscript 41399-Review.docx
Peer-review Report 41399-Peer-review(s).pdf
Answering Reviewers 41399-Answering reviewers.pdf
Scientific Misconduct Check 41399-Scientific misconduct check.pdf
Scientific Editor Work List 41399-Scientific editor work list.pdf
Audio Core Tip 41399-Audio core tip.mp3
Biostatistics Review Certificate 41399-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 41399-Conflict-of-interest statement.pdf
Copyright License Agreement 41399-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 41399-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 41399-Language certificate.pdf