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12/5/2018 5:49:59 PM | Browse: 362 | Download: 264
Publication Name World Journal of Biological Chemistry
Manuscript ID 42037
Country Italy
Category Biochemistry & Molecular Biology
Manuscript Type Editorial
Article Title New findings showing how DNA methylation influences diseases
Manuscript Source Invited Manuscript
All Author List Fabio Sallustio, Loreto Gesualdo and Anna Gallone
Funding Agency and Grant Number
Corresponding Author Fabio Sallustio, MSc, PhD, Assistant Professor, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Piazza G. Cesare, 11, Bari 70124, Bari 70121, Italy. fabio.sallustio@uniba.it
Key Words DNA methylation; Stem cells; Enhancer; IgA nephropathy; Gene regulation
Core Tip DNA methylation in eukaryotes acts as a hereditary regulation mechanism that influences gene expression and cell differentiation. Recently, we have begun to understand that the features of DNA methylation are not the same for all the cells. Major differences have been found between differentiated cells and stem cells. However, epigenetic modifications may take place throughout life and influence various diseases, and they are very important for improving the understanding of pathogenic mechanisms. New studies show that DNA methylation can also influence diseases that do not appear to be related to the environment.
Citation Sallustio F, Gesualdo L, Gallone A. New findings showing how DNA methylation influences diseases. World J Biol Chem 2019; 10(1): 1-6
Received
2018-09-05 00:19
Peer-Review Started
2018-09-06 01:34
To Make the First Decision
2018-09-11 10:01
Return for Revision
2018-09-12 01:25
Revised
2018-10-01 11:14
Second Decision
2018-12-03 01:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-05 17:49
Articles in Press
2018-12-05 17:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-12-09 22:55
Typeset the Manuscript
2018-12-24 08:00
ISSN 1949-8454 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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