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12/5/2018 5:40:54 AM | Browse: 805 | Download: 335
Publication Name World Journal of Hepatology
Manuscript ID 42601
Country/Territory Denmark
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects
Manuscript Source Invited Manuscript
All Author List Tea L Laursen, Christoffer A Hagemann, Chunshan Wei, Konstantin Kazankov, Karen L Thomsen, Filip K Knop and Henning Gronbaek
Funding Agency and Grant Number
Corresponding Author Henning Gronbaek, MD, PhD, Professor, Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, Entrance C, Level 1, C116, Aarhus N DK-8200, Denmark. henngroe@rm.dk
Key Words Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Bariatric surgery; Insulin resistance, Gut hormones; Glucagon-like peptide 1; Steatosis; Inflammation; Fibrosis
Core Tip Non-alcoholic fatty liver disease (NAFLD) is a significant liver disease with risks of steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD and NASH are closely related to obesity, the metabolic syndrome, and type 2 diabetes (T2D). Bariatric surgery induces weight loss and improves the features of the metabolic syndrome and T2D. Surgery may reverse pathological liver changes. In the present review, we focus on the primary effects of bariatric surgery on metabolic pathways and systematically reviews the effects of bariatric surgery on changes in liver disease severity in NAFLD and NASH patients.
Citation Laursen TL, Hagemann CA, Wei C, Kazankov K, Thomsen KL, Knop FK, Grønbæk H. Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects. World J Hepatol 2019; 11(2): 138-149
Received
2018-10-05 02:38
Peer-Review Started
2018-10-06 00:16
To Make the First Decision
2018-10-29 03:07
Return for Revision
2018-10-31 07:40
Revised
2018-11-01 10:21
Second Decision
2018-11-30 08:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-05 05:40
Articles in Press
2018-12-05 05:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-02-24 06:12
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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