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Publication Name World Journal of Hepatology
Manuscript ID 42636
Country of Manuscript Source China
Specialty Gastroenterology and Hepatology
Manuscript Type Review
Article Title Colorectal liver metastases: An update on multidisciplinary approach
Manuscript Source Invited Manuscript
All Author List Felix Che-Lok Chow and Kenneth Siu-Ho Chok
Funding Agency and Grant Number
Correspondence To Kenneth Siu-Ho Chok, FRCS (Ed), Associate Professor, Department of Surgery and State Key Laboratory for Liver Research, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong , China. Chok6275@hku.hk
Keywords Colorectal cancer; Liver metastases; Hepatic resection; Neoadjuvant therapy; Adjuvant chemotherapy; Intra-arterial therapy; Precision medicine; Multidisciplinary approach
Core Tip Surgery offers the only hope of cure in colorectal liver metastasis. It can be performed if complete metastasectomy is attainable. There is no consensus on the ideal management strategy for synchronous disease. A subset of patients presenting with unresectable disease may become eligible for resection after liver remnant augmentation or conversion therapy (chemo-therapeutics +/- biological agents). Amid increasing application of loco-regional therapies to colorectal liver metastasis, their role in the treatment paradigm remains to be defined. Refined patient selection – with greater emphasis on tumour biology – is essential to improving treatment outcome. The multidisciplinary approach helps determine the optimal treatment strategy from an expanding armamentarium of therapeutic options for each patient.
Citation Chow FCL, Chok KSH. Colorectal liver metastases: An update on multidisciplinary approach. World J Hepatol 2018; In press
Received
2018-10-05 02:39
Peer-Review Started
2018-10-06 00:14
To Make the First Decision
2018-11-16 01:43
Return for Revision
2018-11-21 03:07
Revised
2018-11-24 03:54
Second Decision
2018-12-03 00:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-05 05:56
Articles in Press
2018-12-05 05:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Fang-Fang Ji
Reviewer Code 02528812, 00071640, and 02860874
Editorial Director Jin-Lei Wang
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Revised Manuscript 42636-Review.docx
Peer-review Report 42636-Peer-review(s).pdf
Answering Reviewers 42636-Answering reviewers.pdf
Scientific Misconduct Check 42636-Scientific misconduct check.pdf
Scientific Editor Work List 42636-Scientific editor work list.pdf
Audio Core Tip 42636-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 42636-Conflict-of-interest statement.pdf
Copyright License Agreement 42636-Copyright assignment.pdf