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1/11/2019 1:00:47 AM | Browse: 494 | Download: 473
Publication Name World Journal of Stem Cells
Manuscript ID 42776
Country/Territory Germany
Category Dentistry, Oral Surgery & Medicine
Manuscript Type Case Report
Article Title Improved guided bone regeneration by combined application of unmodified, fresh autologous adipose derived regenerative cells and plasma rich in growth factors: A first-in-human case report and literature review
Manuscript Source Unsolicited Manuscript
All Author List Önder Solakoglu, Werner Götz, Maren C Kiessling, Christopher Alt, Christoph Schmitz and Eckhard U Alt
Funding Agency and Grant Number
Corresponding Author Önder Solakoglu, DDS, MSc, PhD, Adjunct Professor, Surgeon, Clinic for Periodontology and Implantology, Martinistr. 52, Hamburg 22453, Germany. solakoglu@fpi-hamburg.de
Key Words Case report; Cell-based therapy; Guided bone regeneration; Maxillary sinus augmentation; Lateral alveolar ridge augmentation; Unmodified autologous adipose-derived regenerative cells; Stem cells
Core Tip Novel strategies are needed in oral surgery for improving guided bone regeneration in maxillary sinus augmentation (GBR-MSA) prior to implant placement. We demonstrate that in GBR-MSA the combination of freshly isolated, unmodified autologous adipose-derived regenerative cells, fraction 2 of plasma rich in growth factors (PRGF-2) and an osteoinductive scaffold (OIS) is superior to the combination of PRGF-2 and the same OIS alone. This novel procedure might contribute to decrease the healing period and increase bone quality in rehabilitation of the edentulous posterior maxilla as well as in other regenerative techniques in pre-implant bone augmentation procedures.
Citation Solakoglu Ö, Götz W, Kiessling MC, Alt C, Schmitz C, Alt EU. Improved guided bone regeneration by combined application of unmodified, fresh autologous adipose derived regenerative cells and plasma rich in growth factors: A first-in-human case report and literature review. World J Stem Cells 2019; 11(2): 124-146
Received
2018-10-09 08:10
Peer-Review Started
2018-10-09 11:04
To Make the First Decision
2018-11-16 01:38
Return for Revision
2018-11-19 08:12
Revised
2018-12-07 07:26
Second Decision
2019-01-08 12:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-11 01:00
Articles in Press
2019-01-11 01:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-01-23 19:01
Typeset the Manuscript
2019-02-25 10:21
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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