| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Treatment for gastric ‘indefinite for neoplasm/dysplasia’ lesions based on predictive factors
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mi Jung Kwon, Ho Suk Kang, Hyeon Tae Kim, Jin Woo Choo, Bho Hyeon Lee, Sung Eun Hong, Kun Ha Park, Dong Min Jung, Jae Seung Soh, Hyun Lim, Sung Hoon Moon, Jong Hyeok Kim, HR Park, Soo Kee Min, Jin won Seo and Ji-Young Choe |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Ho Suk Kang, MD, MSc, Assistant Professor, Doctor, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, 22 Gwanpyeong-ro 170-gil, Dongan-gu, Anyang 14068, Gyeonggi-do, South Korea. hskang76@hallym.or.kr |
| Key Words |
Gastric cancer; Biopsy; Endoscopic surgical procedure; Diagnostic delay; Prognosis |
| Core Tip |
At initial biopsy, ‘indefinite for neoplasm/dysplasia’ (IFND) lesions proved to be adenocarcinomas (22.6%). Independent risk factors for gastric IFND cancer were age (≥ 60 years), endoscopic size (≥ 10 mm), single lesion, spontaneous bleeding, atypical epithelia, and repeated IFND diagnosis. Additionally, fold change predicted undifferentiated or invasive carcinoma in the submucosal layers or deeper. However, diagnostic delays shorter than 1 year were not associated with worse prognoses. In summary, for IFND lesions with these features, endoscopic resection may be a better option than repeated endoscopic biopsy. In the absence of associated risk factors, accurate diagnosis through follow-up within 1 year is recommended. |
| Citation |
Kwon MJ, Kang HS, Kim HT, Choo JW, Lee BH, Hong SE, Park KH, Jung DM, Lim H, Soh JS, Moon SH, Kim JH, Park HR, Min SK, Seo JW, Choe JY. Treatment for gastric ‘indefinite for neoplasm/dysplasia’ lesions based on predictive factors. World J Gastroenterol 2019; 25(4): 469-484 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
