Publication Name	World Journal of Gastroenterology
Manuscript ID	43097
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Serum hepatitis B virus RNA is a predictor of HBeAg seroconversion and virological response with entecavir treatment in chronic hepatitis B patients
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Luo, Xia-Xia Zhang, Li-Hua Cao, Ning Tan, Qian Kang, Hong-Li Xi, Min Yu and Xiao-Yuan Xu
Funding Agency and Grant Number	Funding Agency Grant Number the 13th Five-Year Plan 2018ZX09206005-002
Corresponding Author	Xiao-Yuan Xu, MD, Professor, Department of Infectious Diseases, Peking University First Hospital, Xishiku Street 8, Beijing 100034, China. xiaoyuanxu6@163.com
Key Words	Chronic hepatitis B; Hepatitis B virus RNA; Virological response; HBeAg seroconversion; Entecavir
Core Tip	HBeAg seroconversion was more likely to be achieved for chronic hepatitis B patients with hepatitis B virus (HBV) RNA levels below 4.12 log10 copies/mL before treatment. In the partial virological response group, serum HBV RNA showed an increasing trend.
Citation	Luo H, Zhang XX, Cao LH, Tan N, Kang Q, Xi HL, Yu M, Xu XY. Serum hepatitis B virus RNA is a predictor of HBeAg seroconversion and virological response with entecavir treatment in chronic hepatitis B patients. World J Gastroenterol 2019; 25(6): 719-728

Received	2018-11-05 02:52
Peer-Review Started	2018-11-05 09:29
To Make the First Decision	2018-12-29 01:04
Return for Revision	2018-12-29 02:20
Revised	2019-01-11 15:17
Second Decision	2019-01-18 11:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-01-18 23:03
Articles in Press	2019-01-18 23:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-01-24 08:40
Typeset the Manuscript	2019-02-13 09:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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