Publication Name	World Journal of Stem Cells
Manuscript ID	43272
Country	Canada

Category	Cell Biology
Manuscript Type	Review
Article Title	Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes
Manuscript Source	Invited Manuscript
All Author List	Pranav Machiraju and Steven C Greenway
Funding Agency and Grant Number	Funding Agency Grant Number Children’s Cardiomyopathy Foundation 2017
Corresponding Author	Steven C Greenway, Section of Cardiology, Alberta Children’s Hospital, 28 Oki Drive NW, Calgary T3B 6A8, Canada. steven.greenway@ahs.ca
Key Words	Induced pluripotent stem cells; Induced pluripotent stem cell-derived cardiomyocytes; Regenerative medicine; Stem cell biology; Translational research
Core Tip	Induced pluripotent stem cells are key for generating disease-, patient-, and tissue-specific in vitro models. As such, induced pluripotent stem cells differentiated into cardiomyocytes offer a potential tool for the understanding of disease and the development of life-saving therapeutics. Currently, cardiomyocytes can be differentiated with high efficiency but remain immature in their structure and function. Maturation of these cells is possible using a variety of approaches and will allow for more accurate disease modeling.
Citation	Machiraju P, Greenway SC. Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes. World J Stem Cells 2019; 11(1): 33-43

Received	2018-10-30 08:44
Peer-Review Started	2018-10-30 10:11
To Make the First Decision	2018-11-16 01:37
Return for Revision	2018-11-19 08:14
Revised	2018-11-24 18:53
Second Decision	2019-01-08 13:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-01-10 16:05
Articles in Press	2019-01-10 16:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-01-22 06:49

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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