Publication Name	World Journal of Hypertension
Manuscript ID	44533
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Achieving control of resistant hypertension: Not just the number of blood pressure medications
Manuscript Source	Invited Manuscript
All Author List	Kara Schmidt, William Kelley, Steven Tringali and Jian Huang
Funding Agency and Grant Number
Corresponding Author	Jian Huang, FACP, MD, Attending Doctor, Professor, Department of Internal Medicine, University of California San Francisco-Fresno Medical Education Program, 2615 E Clinton Ave, Fresno, CA 93703, United States. jian.huang@va.gov
Key Words	Resistant hypertension; Pseudoresistance; Mineralocorticoid receptor antagonists; Device-based hypertension treatment; Renal denervation; Carotid baroreceptor activation therapy; Central arteriovenous anastomosis
Core Tip	Resistant hypertension (RH) is associated with an increased risk of cardiovascular events as well as mortality. Updated American College of Cardiology and American Heart Association guidelines in 2017 promote the use of mineralocorticoid receptor antagonists, which is a major change from prior guidelines. Device-based therapies such as renal denervation and carotid baroreceptor activation have emerged as innovative treatment modalities. They are continuing to be refined to improve their safety as well as efficacy profiles. Overall more validation is needed for device-based therapies, especially in the RH population.
Citation	Schmidt K, Kelley W, Tringali S, Huang J. Achieving control of resistant hypertension: Not just the number of blood pressure medications. World J Hypertens 2019; 9(1): 1-16

Received	2018-11-14 04:06
Peer-Review Started	2018-11-14 09:28
To Make the First Decision	2018-11-28 05:59
Return for Revision	2018-12-05 03:06
Revised	2019-01-11 18:23
Second Decision	2019-01-16 09:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-01-22 04:42
Articles in Press	2019-01-22 04:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-03-01 10:12

ISSN	2220-3168 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com