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Publication Name World Journal of Clinical Cases
Manuscript ID 45324
Country of Manuscript Source China
Specialty Medicine, Research and Experimental
Manuscript type Case Report
Article Title Small cell lung cancer with panhypopituitarism due to ectopic adrenocorticotropic hormone syndrome: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ting Jin, Fang Wu, Shui-Ya Sun, Fen-Ping Zheng, Jia-Qiang Zhou, Yi-Ping Zhu and Zhou Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Foundation for Youth 30800533
Public Welfare Project of Science and Technology Department of Zhejiang Province, China 2017C33056
Correspondence To Zhou Wang, MD, Professor, Department of Endocrinology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, 3 East Qing Chun Road, Hangzhou 310016, Zhejiang Province, China. 3405008@zju.edu.cn
Keywords Small cell lung cancer; Ectopic adrenocorticotropic hormone syndrome; Panhypopituitarism; Case report
Core Tip Ectopic adrenocorticotropic hormone syndrome (EAS) is the common paraneoplastic disorder in patients with small cell lung cancer (SCLC). However, it is uncommon that EAS has an influence on hypothalamus-pituitary function. Here, we report a rare case of SCLC complicated with panhypopituitarism due to EAS. We hypothesize that EAS induced high levels of serum glucocorticoid and negative feedback for the synthesis and secretion of antidiuretic hormone from the paraventricular nucleus, and trophic hormones from the anterior pituitary.
Citation Jin T, Wu F, Sun SY, Zheng FP, Zhou JQ, Zhu YP, Wang Z. Small cell lung cancer with panhypopituitarism due to ectopic adrenocorticotropic hormone syndrome: A case report. World J Clin Cases 2019; 7(10): 1177-1183
Received
2018-12-29 05:18
Peer-Review Started
2018-12-29 15:07
To Make the First Decision
2019-03-14 00:13
Return for Revision
2019-03-19 02:30
Revised
2019-03-29 04:35
Second Decision
2019-04-08 07:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-09 20:15
Articles in Press
2019-04-09 20:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-04-16 18:17
Typeset the Manuscript
2019-05-24 03:32
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Fang-Fang Ji (Quit in 2019)
Reviewer Code 03086186, and 02445408
Editorial Director Jin-Lei Wang
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Donna Fox
Electronic Editor Yun-Xiaojian Wu
Responsible Electronic Editor Yun-Xiaojian Wu
Responsible Science Editor Jin-Lei Wang
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJCC-7-1177.pdf
Full Article (Word) WJCC-7-1177.docx
Manuscript File 45324-Review.docx
Answering Reviewers 45324-Answering reviewers.pdf
Audio Core Tip 45324-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 45324-Conflict-of-interest statement.pdf
Copyright License Agreement 45324-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45324-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 45324-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 45324-Language certificate.pdf
Peer-review Report 45324-Peer-review(s).pdf
Scientific Misconduct Check 45324-Scientific misconduct check.pdf
Scientific Editor Work List 45324-Scientific editor work list.pdf