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3/12/2019 3:40:58 PM | Browse: 114 | Download: 12
Publication Name World Journal of Hepatology
Manuscript ID 45419
Country of Manuscript Source Romania
Specialty Surgery
Manuscript type Observational Study
Article Title Angiogenesis of hepatocellular carcinoma: An immunohistochemistry study
Manuscript Source Invited Manuscript
All Author List Decebal Fodor, Ioan Jung, Sabin Turdean, Catalin Satala and Simona Gurzu
Funding Agency and Grant Number
Correspondence To Simona Gurzu, MD, PhD, Chief Doctor, Doctor, Full Professor, Professor, Professor, Consulting Pathologist, Department of Pathology, University of Medicine, Pharmacy, Sciences and Technology, 38 Gheorghe Marinescu Street, Targu Mures 540139, Romania. simonagurzu@yahoo.com
Keywords Hepatocellular carcinoma; Angiogenesis; Endothelial area; Antiangiogenic therapy
Core Tip In this paper we showed a possible role of morphological and immunohistochemical features of Hepatocellular carcinoma (HCC) in predicting the individualized antiangiogenic therapy of HCC. Based on the results and literature data, it seems that dedifferentiated HCCs developed in non-cirrhotic liver are predominantly driven via Cyclooxygenase-2 axis, whereas vascular endothelial growth factor-A induces hepatocarcinogenesis in patients with HCCs developed on the cirrhosis background.
Citation Fodor D, Jung I, Turdean S, Satala C, Gurzu S. Angiogenesis of hepatocellular carcinoma: An immunohistochemistry study. World J Hepatol 2019; 11(3): 294-304
2018-12-28 09:26
Peer-Review Started
2018-12-29 01:15
To Make the First Decision
2019-01-25 00:20
Return for Revision
2019-01-27 01:18
2019-02-22 16:21
Second Decision
2019-03-08 08:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-12 15:40
Articles in Press
2019-03-12 15:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-03-27 05:35
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Ruo-Yu Ma
Reviewer Code 00006459, 03478254, 02439215, and 01437833
Editorial Director Jin-Lei Wang
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Electronic Editor Yan-Liang Zhang
Responsible Electronic Editor Yan-Liang Zhang
Responsible Science Editor Ya-Juan Ma
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJH-11-294.pdf
Full Article (Word) WJH-11-294.docx
Manuscript File 45419-Review.doc
Answering Reviewers 45419-Answering reviewers.pdf
Audio Core Tip 45419-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 45419-Conflict-of-interest statement.pdf
Copyright License Agreement 45419-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 45419-Institutional review board statement.pdf
Peer-review Report 45419-Peer-review(s).pdf
Scientific Misconduct Check 45419-Scientific misconduct check.pdf
Scientific Editor Work List 45419-Scientific editor work list.pdf