Publication Name	World Journal of Clinical Cases
Manuscript ID	45782
Country	China

Category	Neuroimaging
Manuscript Type	Observational Study
Article Title	Value of superb micro-vascular imaging in predicting ischemic stroke in patients with carotid atherosclerotic plaques
Manuscript Source	Unsolicited Manuscript
All Author List	De-Bin Yang, Jie Zhou, Lan Feng, Rong Xu and Ying-Chun Wang
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Jiading District Health and Family Planning Commission Health Planning Commission Scientific Research Project KYXM, 2015-KY-02
Corresponding Author	Ying-Chun Wang, MD, Chief Doctor, Department of Ultrasonic Imaging, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences, No. 1 Chengbei Road, Shanghai 201800, China. wangyingchun4478@163.com
Key Words	Superb micro-vascular imaging; Contrast-enhanced ultrasound; Carotid atherosclerotic plaques; Ischemic stroke
Core Tip	Unstable carotid plaques are easily raptured leading to the occurrence of ischemic stroke. Contrast-enhanced ultrasound (CEUS) is currently the primary means of assessing plaque stability. However, CEUS cannot be used for screening for unstable plaques. Superb micro-vascular imaging (SMI) is able to check for low-speed blood flow in the plaque and is expected to be a screening tool for unstable plaques. This study found that the area under curve of SMI predicting ischemic stroke in patients with plaque is 0.878, with a sensitivity of 86.05% and a specificity of 79.27%. SMI level II can be used for predicting ischemic stroke.
Citation	Yang DB, Zhou J, Feng L, Xu R, Wang YC. Value of superb micro-vascular imaging in predicting ischemic stroke in patients with carotid atherosclerotic plaques. World J Clin Cases 2019; 7(7): 839-848

Received	2019-01-16 01:52
Peer-Review Started	2019-01-16 04:40
To Make the First Decision	2019-03-14 00:19
Return for Revision	2019-03-14 01:00
Revised	2019-03-14 05:22
Second Decision	2019-03-15 09:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-03-16 22:41
Articles in Press	2019-03-16 22:41
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-03-26 17:48
Typeset the Manuscript	2019-04-04 07:37

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com