Publication Name	World Journal of Clinical Cases
Manuscript ID	45834
Country	China

Category	Orthopedics
Manuscript Type	Meta-Analysis
Article Title	Efficacy and safety of tranexamic acid in intertrochanteric fractures: An updated meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Xin-Die Zhou, Jin Li, Guo-Ming Fan, Yong Huang and Nan-Wei Xu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81702179 Major Scientific and Technological Project of Changzhou Municipal Commission of Health and Family Planning ZD201809
Corresponding Author	Yong Huang, MD, Doctor, Full Professor, Department of Orthopedics Surgery, The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China., Department of Orthopedics, The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China., Changzhou 213000, China. huangyong@njmu.edu.cn
Key Words	Tranexamic acid; Intertrochanteric fracture; Blood loss; Randomized controlled trial; Meta-analysis
Core Tip	Intertrochanteric fracture (ITF) is a common type of injury in the elderly population. Though minimal invasive surgical therapy has been routinely performed, the overall blood loss volume may still be much larger than that observed. Tranexamic acid (TXA) has been wildly used in reducing surgical bleeding, however, the paucity of studies regarding its use in ITF surgery has limited its integration into this field. Thus, in order to investigate the efficacy and safety of TXA administration in elderly ITF patients, we meta-analyzed relevant literatures regarding the potential risks and benefits of TXA in ITF surgery.
Citation	Zhou XD, Li J, Fan GM, Huang Y, Xu NW. Efficacy and safety of tranexamic acid in intertrochanteric fractures: An updated meta-analysis. World J Clin Cases 2019; 7(11): 1302-1314

Received	2019-01-22 01:34
Peer-Review Started	2019-01-23 09:49
To Make the First Decision	2019-01-27 05:31
Return for Revision	2019-02-14 02:21
Revised	2019-02-15 10:33
Second Decision	2019-03-15 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-03-16 22:38
Articles in Press	2019-03-16 22:38
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-03-22 13:54
Typeset the Manuscript	2019-06-06 03:00

ISSN	2307-8960 (online)
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