Publication Name	World Journal of Gastroenterology
Manuscript ID	45845
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Systematic review with meta-analysis on transplantation for alcohol-related liver disease: Very low evidence of improved outcomes
Manuscript Source	Invited Manuscript
All Author List	Nicole T Shen, Cristina Londono, Stephanie L Gold, Ashley Wu, Keith C Mages and Robert S Brown Jr
Funding Agency and Grant Number	Funding Agency Grant Number Agency for Healthcare Research and Quality T32HS 000066
Corresponding Author	Nicole T Shen, MD, MSc, Academic Fellow, Academic Research, Doctor, Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, 1305 York Avenue 4th Floor, New York, NY 10021, United States. nts9004@nyp.org
Key Words	Alcohol-related hepatitis; Alcohol-related cirrhosis; Alcohol use disorder; Liver transplantation; Standardization
Core Tip	Our findings suggest the dearth of well-published literature on transplantation in alcohol-related liver disease (ALD) and the urgent need for rigorous standardization in studying ALD. Such standardization would enable global scale assessment on the efficacy of transplanting ALD. Standardization should include addressing the presence and treatment of alcohol use disorder, the clinical definition of ALD, reporting the spectrum of the population studied (acute, chronic, acute on chronic, hepatocellular carcinoma in the setting of ALD), data collection, and definition and detection of relapse.
Citation	Shen NT, Londono C, Gold S, Wu A, Mages KC, Brown RS Jr. Systematic review with meta-analysis on transplantation for alcohol-related liver disease: Very low evidence of improved outcomes. World J Gastroenterol 2019; 25(13): 1628-1639

Received	2019-02-06 04:18
Peer-Review Started	2019-02-06 13:34
To Make the First Decision	2019-02-21 05:52
Return for Revision	2019-02-21 08:35
Revised	2019-03-07 03:09
Second Decision	2019-03-08 08:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-03-12 04:28
Articles in Press	2019-03-12 04:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-04-02 00:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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