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4/11/2019 1:33:59 AM | Browse: 316 | Download: 310
Publication Name World Journal of Gastroenterology
Manuscript ID 46401
Country/Territory China
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Alteration of the esophageal microbiota in Barrett's esophagus and esophageal adenocarcinoma
Manuscript Source Invited Manuscript
All Author List Jing Lv, Lei Guo, Ji-Jun Liu, He-Ping Zhao, Jun Zhang and Ji-Han Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81702067
Shaanxi Natural Science Foundation of China 2018JQ8029
Shaanxi Natural Science Foundation of China 2017JQ8041
Corresponding Author Ji-Han Wang, PhD, Doctor, Postdoc, Department of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, No.555 You Yi Dong Road, Xi'an 710054, Shaanxi Province, China. 513837742@qq.com
Key Words Barrett's esophagus; Esophageal adenocarcinoma; Microorganisms; Esophageal microbiota; Alteration; Dysbiosis
Core Tip Esophageal adenocarcinoma (EAC) is a malignancy with poor prognosis, and Barrett's esophagus (BE) is the only recognized precursor. As part of the human gut, the esophagus harbours distinctive microbiota, and dysbiosis may be related to BE/EAC. Many studies have attempted to demonstrate the esophageal microbiota in the normal esophagus and in different diseases, but more data is required. Studies on the esophageal microbiota in BE/EAC have mainly concentrated on these associations, and the underlying mechanisms remain blurred. This review focuses on the features and associations of esophageal microbiota and BE/EAC, which might provide some evidence of their relations.
Citation Lv J, Guo L, Liu JJ, Zhao HP, Zhang J, Wang JH. Alteration of the esophageal microbiota in Barrett's esophagus and esophageal adenocarcinoma. World J Gastroenterol 2019; 25(18): 2149-2161
Received
2019-02-12 01:49
Peer-Review Started
2019-02-14 13:16
To Make the First Decision
2019-03-20 06:42
Return for Revision
2019-03-21 07:04
Revised
2019-03-27 04:51
Second Decision
2019-04-04 08:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-11 01:33
Articles in Press
2019-04-11 01:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-04-16 17:20
Typeset the Manuscript
2019-05-14 00:30
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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