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Publication Name World Journal of Gastroenterology
Manuscript ID 46439
Country of Manuscript Source China
Specialty Gastroenterology and Hepatology
Manuscript type Retrospective Study
Article Title Clinical value of preoperative methylated septin 9 in Chinese colorectal cancer patients
Manuscript Source Unsolicited Manuscript
All Author List Xue Yang, Zhi-Jie Xu, Xi Chen, Shuang-Shuang Zeng, Long Qian, Jie Wei, Mei Peng, Xiang Wang, Wan-Li Liu, Hong-Ying Ma, Zhi-Cheng Gong and Yuan-Liang Yan
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 81803035, 81703036, 81572946
the China Postdoctoral Science Foundation 2017M610510
Youth Fund of Xiangya Hospital 2017Q17
the Postdoctoral Science Foundation of Central South University 185702
Correspondence To Zhi-Cheng Gong, PhD, Academic Fellow, Chief Pharmacist, Professor, Department of Pharmacy, Institute for Rational and Safe Medication Practices, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha 410008, Hunan Province, China. gongzhicheng@csu.edu.cn
Keywords Methylated septin 9; Methylated; Colorectal cancer; Diagnosis; Prognosis
Core Tip This study retrospectively explored the value of serum septin 9 methylation (mSEPT9) in the diagnosis and prognosis of colorectal cancer in a Chinese population. Preoperative mSEPT9 levels in 354 enrolled patients were retrospectively analyzed. In addition, the effects of mSEPT9 on the occurrence and prognosis of 330 colorectal cancer cases from The Cancer Genome Atlas database were evaluated using bioinformatics analyses. Besides, nine meaningful mSEPT9 sites were found to provide guidance for the follow-up studies.
Citation Yang X, Xu ZJ, Chen X, Zeng SS, Qian L, Wei J, Peng M, Wang X, Liu WL, Ma HY, Gong ZC, Yan YL. Clinical value of preoperative methylated septin 9 in Chinese colorectal cancer patients. World J Gastroenterol 2019; 25(17): 2099-2109
Received
2019-02-14 01:28
Peer-Review Started
2019-02-15 09:35
To Make the First Decision
2019-03-06 01:34
Return for Revision
2019-03-08 01:57
Revised
2019-03-25 02:23
Second Decision
2019-04-04 08:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-10 21:26
Articles in Press
2019-04-10 21:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-04-28 00:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Jia-Ping Yan
Reviewer Code 02495872, and 02919626
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor Yu-Jie Ma
Responsible Electronic Editor Yu-Jie Ma
Responsible Science Editor Ze-Mao Gong
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJG-25-2099.pdf
Manuscript File 46439-Review.doc
Answering Reviewers 46439-Answering reviewers.pdf
Audio Core Tip 46439-Audio core tip.wav
Biostatistics Review Certificate 46439-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 46439-Conflict-of-interest statement.pdf
Copyright License Agreement 46439-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46439-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 46439-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 46439-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 46439-Language certificate.pdf
Supplementary Material 46439-Supplementary material.pdf
Peer-review Report 46439-Peer-review(s).pdf
Scientific Misconduct Check 46439-Scientific misconduct check.pdf
Scientific Editor Work List 46439-Scientific editor work list.pdf