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Publication Name World Journal of Psychiatry
Manuscript ID 46491
Country/Territory United States
Category Psychiatry
Manuscript Type Editorial
Article Title Evidence for using pimavanserin for the treatment of Parkinson's disease psychosis
Manuscript Source Invited Manuscript
All Author List Rajesh R Tampi, Deena J Tampi, Juan J Young, Rakin A Hoq, Geetha Manikkara and Silpa Balachandran
Funding Agency and Grant Number
Corresponding Author Rajesh R Tampi, MD, Chairman, Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Cleveland, NH, Ohio 44106, United States. rajesh.tampi@yale.edu
Key Words Pimavanserin; Systematic review; Parkinson’s disease; Parkinson’s disease psychosis; Psychosis; Antipsychotic
Core Tip Pimavanserin is an atypical antipsychotic that was the first medication to be approved by the Food and Drug Administration for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis (PDP). There are only two published tri-als that have evaluated the use of pimavanserin among individuals with PDP. Both studies are of good quality and found that pimavanserin improves psychotic symp-toms among individuals with PDP when compared to placebo. Additionally, pimavan-serin was fairly well tolerated in both studies and did not appear to cause significant sedation or worsen motor symptoms among individuals with PDP.
Citation Tampi RR, Tampi DJ, Young JJ, Balachandran S, Hoq RA, Manikkara G. Evidence for using pimavanserin for the treatment of Parkinson's disease psychosis. World J Psychiatr 2019; 9(3): 47-54
Received
2019-02-14 06:25
Peer-Review Started
To Make the First Decision
2019-03-08 01:11
Return for Revision
2019-03-08 01:48
Revised
2019-04-23 07:06
Second Decision
2019-05-10 09:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-11 15:09
Articles in Press
2019-05-11 15:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-06-05 23:54
ISSN 2220-3206 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights re-served.
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