Publication Name	World Journal of Gastroenterology
Manuscript ID	46670
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatocellular carcinoma: Mechanisms of progression and immunotherapy
Manuscript Source	Invited Manuscript
All Author List	Yu Jiang, Qiu-Ju Han and Jian Zhang
Funding Agency and Grant Number
Corresponding Author	Jian Zhang, PhD, Professor, Institute of Immunopharmaceutical Sciences, School of Pharmaceutical Sciences, Shandong University, 44 Wenhua West Road, Jinan 250012, Shandong Province, China. zhangj65@sdu.edu.cn
Key Words	Hepatocellular carcinoma; Mechanisms; Immunotherapy
Core Tip	Among all primary liver cancers, hepatocellular carcinoma (HCC) is the most common and accounts for 90% of cases. Mechanisms related to HCC progression and treatment strategies have been extensively reported. In this paper, we reviewed the molecular mechanisms involved in the progression of HCC and the latest advancements in immunotherapy by combining the research progress and results from our laboratory in recent years.
Citation	Jiang Y, Han QJ, Zhang J. Hepatocellular carcinoma: Mechanisms of progression and immunotherapy. World J Gastroenterol 2019; 25(25): 3151-3167

Received	2019-03-06 07:06
Peer-Review Started	2019-03-06 08:09
To Make the First Decision	2019-04-17 00:49
Return for Revision	2019-04-17 02:37
Revised	2019-04-28 12:14
Second Decision	2019-05-17 08:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-05-18 12:47
Articles in Press	2019-05-18 12:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-05-29 20:03
Typeset the Manuscript	2019-07-04 07:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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