Publication Name	World Journal of Clinical Cases
Manuscript ID	46752
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Basic Study
Article Title	Elevated levels of interleukin-1β, interleukin-6, tumor necrosis factor-α and vascular endothelial growth factor in patients with knee articular cartilage injury
Manuscript Source	Unsolicited Manuscript
All Author List	Zhen-Wei Wang, Le Chen, Xiao-Rui Hao, Zhen-An Qu, Shi-Bo Huang, Xiao-Jun Ma, Jian-Chuan Wang and Wei-Ming Wang
Funding Agency and Grant Number
Corresponding Author	Wei-Ming Wang, BSc, MD, PhD, Doctor, Professor, Department of Sports Medicine, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Jie, Zhongshan District, Dalian 116001, Liaoning Province, China. wangwm_01@126.com
Key Words	Knee articular cartilage injury; Interleukin-1β; Interleukin-6; Tumor necrosis factor-α; Vascular endothelial growth factor
Core Tip	Increased levels of interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α and vascular endothelial growth factor are found in patients with knee articular cartilage injury and are associated with the disease severity, suggesting that they might be involved in the pathogenesis of knee articular cartilage injury and therapeutic targeting them might be beneficial for the treatment of knee articular cartilage injury.
Citation	Wang ZW, Chen L, Hao XR, Qu ZA, Huang SB, Ma XJ, Wang JC, Wang WM. Elevated levels of interleukin-1β, interleukin-6, tumor necrosis factor-α and vascular endothelial growth factor in patients with knee articular cartilage injury. World J Clin Cases 2019; 7(11): 1262-1269

Received	2019-02-22 01:21
Peer-Review Started	2019-02-24 01:12
To Make the First Decision	2019-03-14 00:14
Return for Revision	2019-03-14 07:51
Revised	2019-03-25 00:21
Second Decision	2019-03-28 00:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-04-09 17:00
Articles in Press	2019-04-09 17:00
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-04-21 15:38
Typeset the Manuscript	2019-06-05 09:55

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com