Publication Name	World Journal of Clinical Oncology
Manuscript ID	47069
Country	United States

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Predictors of distant metastasis in acinic cell carcinoma of the parotid gland
Manuscript Source	Invited Manuscript
All Author List	Syed Ahmed Ali, Kevin J Kovatch, Jonah Yousif, Sonali Gupta, Andrew J Rosko and Matthew E Spector
Funding Agency and Grant Number
Corresponding Author	Matthew E Spector, MD, Associate Professor, Attending Doctor, Doctor, Surgeon, Department of Otolaryngology – Head and Neck Surgery, Michigan Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48104, United States. mspector@med.umich.edu
Key Words	Acinic cell carcinoma; Parotid gland; Distant metastases; Facial nerve; Perineural invasion;
Core Tip	This is a retrospective study to evaluate clinical outcomes in patients with primary acinic cell carcinoma of the parotid gland treated at a tertiary care medical center. Among 55 primary cases, 6 patients developed lung metastases. These patients uniformly demonstrated gross facial nerve invasion intraoperatively. Additional factors that were associated with worse disease-free survival and overall survival included higher T-classification and high-grade disease on pathology.
Citation	Ali SA, Kovatch KJ, Yousif J, Gupta S, Rosko AJ, Spector ME. Predictors of distant metastasis in acinic cell carcinoma of the parotid gland. World J Clin Oncol 2020; 11(1): 11-19

Received	2019-03-08 02:04
Peer-Review Started	2019-03-11 01:12
To Make the First Decision	2019-04-16 07:46
Return for Revision	2019-05-13 02:41
Revised	2019-10-14 14:52
Second Decision	2019-11-05 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-06 19:14
Articles in Press	2019-11-06 19:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-17 09:43

ISSN	2218-4333 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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