Publication Name	World Journal of Gastroenterology
Manuscript ID	47271
Country	Germany

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Immunotherapy with dendritic cells and cytokine-induced killer cells for hepatocellular carcinoma: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Jing Cao, Fan-Hua Kong, Xi Liu and Xiao-Bo Wang
Funding Agency and Grant Number
Corresponding Author	Xiao-Bo Wang, MD, Surgeon, Department of surgery, Technical University of Munich, Arcisstrasse 21, Munich 80333, Germany. xiaobo.wang@tum.de
Key Words	Hepatocellular carcinoma; Immunotherapy; Dendritic cells; Cytokine-induced killer cells
Core Tip	Liver cancer, approximately 75% of which is ascribed to hepatocellular carcinoma, has been revealed as the second common cause of cancer-related death worldwide. Though several analyses have supported the effective benefit of cellular immunotherapy when combined with specific hepatocellular carcinoma (HCC) treatment, the efficacy and necessity of cellular immunotherapy after different interventional therapy remains to be interrogated. Our study suggested that the combination of immunotherapy with dendritic cells (DCs), cytokine-induced killer cells (CIKs) and DC-CIK with various routine HCC treatments could evidently improve patients’ prognosis by increasing the overall survival and reduce the recurrence of the malignancy.
Citation	Cao J, Kong FH, Liu X, Wang XB. Immunotherapy with dendritic cells and cytokine-induced killer cells for hepatocellular carcinoma: A meta-analysis. World J Gastroenterol 2019; 25(27): 3649-3663

Received	2019-03-18 02:50
Peer-Review Started	2019-03-18 06:26
To Make the First Decision	2019-04-11 09:02
Return for Revision	2019-04-12 02:51
Revised	2019-04-18 16:21
Second Decision	2019-06-05 10:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-06-08 15:04
Articles in Press	2019-06-08 15:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-06-21 21:23
Typeset the Manuscript	2019-07-17 00:28

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com