BPG is committed to discovery and dissemination of knowledge
Articles in Press
11/6/2019 7:41:05 PM | Browse: 188 | Download: 2
Publication Name World Journal of Clinical Oncology
Manuscript ID 47669
Country of Manuscript Source Uruguay
Specialty Oncology
Manuscript type Systematic Review
Article Title Current concepts in ameloblastoma-targeted therapies in B-raf proto-oncogene serine/threonine kinase V600E mutation: Systematic review
Manuscript Source Invited Manuscript
All Author List Rogelio González-González, Sandra López-Verdín, Jesús Lavalle-Carrasco, Nelly Molina-Frechero, Mario Isiordia-Espinoza, Ramón G Carreón-Burciaga and Ronell Bologna-Molina
Funding Agency and Grant Number
Correspondence To Ronell Bologna-Molina, DDS, MSc, PhD, Postdoc, Professor, Research Scientist, Senior Scientist, Research Scientist, Molecular Pathology, School of Dentistry, Universidad de la República de Uruguay (UDELAR), Las Heras 1925, Montevideo 11600, Montevideo, Uruguay. ronellbologna@odon.edu.uy
Keywords Ameloblastoma; B-raf proto-oncogene serine/threonine kinase; B-raf proto-oncogene serine/threonine kinase V600E; Additional mutations; Targeted therapies;
Core Tip Ameloblastoma is a common neoplasia that is developed from odontogenic epithelium. It is an aggressive and recurrent tumor that can present metastases or malignant transformation. This neoplasia is characterized by presenting different clinical and histological varieties as well as several mutations related to its behavior. Nowadays, there are several studies focused on targeted therapies against the mutations of this tumor, one of the most frequent ones being B-raf proto-oncogene serine/threonine kinase (BRAF) V600E, the treatment of which has been associated with good response. These targeted therapies are suitable for resistant tumors. This study focused on BRAF V600E mutations and its additional mutations and targeted therapies.
Citation González-González R, López-Verdín S, Lavalle-Carrasco J, Molina-Frechero N, Isiordia-Espinoza M, Carreón-Burciaga RG, Bologna-Molina R. Current concepts in ameloblastoma-targeted therapies in B-raf proto-oncogene serine/threonine kinase V600E mutation: Systematic review. World J Clin Oncol 2019; In press
Received
2019-03-23 06:36
Peer-Review Started
2019-03-26 00:40
To Make the First Decision
2019-09-11 00:10
Return for Revision
2019-09-11 09:17
Revised
2019-10-23 19:45
Second Decision
2019-11-05 07:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-11-06 19:41
Articles in Press
2019-11-06 19:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Jia-Ping Yan
Reviewer Code 02929648, and 00209021
Editorial Director Ruo-Yu Ma
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 47669-Review.docx
Answering Reviewers 47669-Answering reviewers.pdf
Audio Core Tip 47669-Audio core tip.mp3
Biostatistics Review Certificate 47669-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 47669-Conflict-of-interest statement.pdf
Copyright License Agreement 47669-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 47669-Language certificate.pdf
Peer-review Report 47669-Peer-review(s).pdf
Scientific Misconduct Check 47669-Scientific misconduct check.pdf
Scientific Editor Work List 47669-Scientific editor work list.pdf