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Publication Name World Journal of Gastroenterology
Manuscript ID 47779
Country of Manuscript Source United States
Specialty Gastroenterology and Hepatology
Manuscript type Review
Article Title G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis
Manuscript Source Invited Manuscript
All Author List Damian Jacenik, Ellen J Beswick, Wanda M Krajewska and Eric R Prossnitz
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Centre, Poland 2017/24/T/NZ5/00045
National Science Centre, Poland 2015/17/N/NZ5/00336
U.S. National Institutes of Health NIH R01 CA163890
U.S. National Institutes of Health NIH R01 CA194496
U.S. National Institutes of Health NIH R01 CA207051
UNM Comprehensive Cancer Center P30 CA118100
Autophagy, Inflammation and Metabolism Center of Biomedical Research Excellence and Dialysis Clinic, Inc. P20 GM121176
Correspondence To Eric R Prossnitz, PhD, Full Professor, Department of Internal Medicine, School of Medicine, and UNM Comprehensive Cancer Center, University of New Mexico, 2325 Camino de Salud, Albuquerque, NM87131, United States. eprossnitz@salud.unm.edu
Keywords G protein-coupled estrogen receptor; Colorectal cancer; Proliferation; Migration; Colonic motility; Inflammatory bowel disease
Core Tip G protein-coupled estrogen receptor (GPER) is a membrane-bound estrogen receptor that participates in the rapid non-genomic actions of estrogens involving numerous downstream signaling pathways. GPER is expressed in the gastrointestinal tract and is engaged in physiological and pathophysiological processes in the colon. This review aims to assess the significance of GPER expression and estrogenic signaling in colorectal carcinogenesis.
Citation Jacenik D, Beswick EJ, Krajewska WM, Prossnitz ER. G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis. World J Gastroenterol 2019; 25(30): 4092-4104
2019-03-28 02:14
Peer-Review Started
2019-03-28 06:09
To Make the First Decision
2019-05-27 00:41
Return for Revision
2019-05-31 00:41
2019-07-03 20:16
Second Decision
2019-07-05 10:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-05 23:46
Articles in Press
2019-07-05 23:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-08-14 07:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Jia-Ping Yan
Reviewer Code 00734047, and 02446061
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor Yan-Liang Zhang
Responsible Electronic Editor Yan-Liang Zhang
Responsible Science Editor Ya-Juan Ma
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJG-25-4092.pdf
Full Article (Word) WJG-25-4092.docx
Manuscript File 47779-Review.docx
Answering Reviewers 47779-Answering reviewers.pdf
Audio Core Tip 47779-Audio core tip.wav
Conflict-of-Interest Disclosure Form 47779-Conflict-of-interest statement.pdf
Copyright License Agreement 47779-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 47779-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 47779-Non-Native Speakers of English Editing Certificate.pdf
Peer-review Report 47779-Peer-review(s).pdf
Scientific Misconduct Check 47779-Scientific misconduct check.pdf
Scientific Editor Work List 47779-Scientific editor work list.pdf