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Articles in Press
7/5/2019 11:46:51 PM | Browse: 390 | Download: 350
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis
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Manuscript Source |
Invited Manuscript |
All Author List |
Damian Jacenik, Ellen J Beswick, Wanda M Krajewska and Eric R Prossnitz |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Science Centre, Poland |
2017/24/T/NZ5/00045 |
National Science Centre, Poland |
2015/17/N/NZ5/00336 |
U.S. National Institutes of Health |
NIH R01 CA163890 |
U.S. National Institutes of Health |
NIH R01 CA194496 |
U.S. National Institutes of Health |
NIH R01 CA207051 |
UNM Comprehensive Cancer Center |
P30 CA118100 |
Autophagy, Inflammation and Metabolism Center of Biomedical Research Excellence and Dialysis Clinic, Inc. |
P20 GM121176 |
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Corresponding Author |
Eric R Prossnitz, PhD, Full Professor, Department of Internal Medicine, School of Medicine, and UNM Comprehensive Cancer Center, University of New Mexico, 2325 Camino de Salud, Albuquerque, NM 87131, United States. eprossnitz@salud.unm.edu |
Key Words |
G protein-coupled estrogen receptor; Colorectal cancer; Proliferation; Migration; Colonic motility; Inflammatory bowel disease |
Core Tip |
G protein-coupled estrogen receptor (GPER) is a membrane-bound estrogen receptor that participates in the rapid non-genomic actions of estrogens involving numerous downstream signaling pathways. GPER is expressed in the gastrointestinal tract and is engaged in physiological and pathophysiological processes in the colon. This review aims to assess the significance of GPER expression and estrogenic signaling in colorectal carcinogenesis. |
Citation |
Jacenik D, Beswick EJ, Krajewska WM, Prossnitz ER. G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis. World J Gastroenterol 2019; 25(30): 4092-4104 |
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Received |
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2019-03-28 02:14 |
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Peer-Review Started |
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2019-03-28 06:09 |
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To Make the First Decision |
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2019-05-27 00:41 |
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Return for Revision |
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2019-05-31 00:41 |
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Revised |
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2019-07-03 20:16 |
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Second Decision |
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2019-07-05 10:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-07-05 23:46 |
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Articles in Press |
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2019-07-05 23:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-14 07:10 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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