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11/7/2019 9:04:45 PM | Browse: 154 | Download: 0
Publication Name World Journal of Orthopedics
Manuscript ID 47803
Country of Manuscript Source Netherlands
Specialty Orthopedics
Manuscript type Retrospective Cohort Study
Article Title Good accuracy of the alpha-defensin lateral flow test for hip periprosthetic joint infection: A pilot study in a retrospective cohort of 52 patients
Manuscript Source Unsolicited Manuscript
All Author List Jesse WP Kuiper, Pieter Pander and Stan J Vos
Funding Agency and Grant Number
Correspondence To Jesse WP Kuiper, MD, MSc, Doctor, Department of Orthopedic Surgery, Noordwest Ziekenhuisgroep, Wilhelminalaan 12, Alkmaar 1815 JD, Netherlands. jwp.kuiper@gmail.com
Keywords Periprosthetic; Arthroplasty; Replacement; Hip; Infection; Periprosthetic joint infection
Core Tip The alpha-defensin lateral flow (ADLF) test is a new diagnostic tool for periprosthetic joint infection (PJI). We evaluated a cohort of 52 patients that underwent aspiration of hip arthroplasty to assess test accuracy. Using Musculoskeletal Infection Society criteria, sensitivity was 100% (CI: 54%-100%) and specificity was 89% (CI: 76%-96%). Using European Bone and Joint Infection Society criteria, sensitivity was lower (71%, CI: 42%-92%) and specificity was higher (97%, CI: 86%-100%), Using 2018 International Consensus Meeting criteria, sensitivity was 91% (62%-100%) and specificity 100% (91%-100%). The results in this cohort are comparable to previous studies.
Citation Kuiper JWP, Pander P, J Vos SJ. Good accuracy of the alpha-defensin lateral flow test for hip periprosthetic joint infection: A pilot study in a retrospective cohort of 52 patients. World J Orthop 2019; In press
Received
2019-03-25 05:29
Peer-Review Started
2019-03-26 01:38
To Make the First Decision
2019-06-12 00:37
Return for Revision
2019-06-20 08:58
Revised
2019-10-18 14:39
Second Decision
2019-11-05 02:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-11-07 21:04
Articles in Press
2019-11-07 21:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-5836 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Ying Dou
Reviewer Code 02454185, and 03068667
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 47803-Review.docx
Answering Reviewers 47803-Answering reviewers.pdf
Audio Core Tip 47803-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 47803-Conflict-of-interest statement.pdf
Copyright License Agreement 47803-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 47803-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 47803-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 47803-Language certificate.pdf
Peer-review Report 47803-Peer-review(s).pdf
Scientific Misconduct Check 47803-Scientific misconduct check.pdf
Scientific Editor Work List 47803-Scientific editor work list.pdf