| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Randomized, double-blinded, placebo-controlled trial evaluating simethicone pretreatment with bowel preparation during colonoscopy
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mohit Rishi, Jaskarin Kaur, Mark Ulanja, Nicholas Manasewitsch, Molly Svendsen, Abubaker Abdalla, Shashank Vemala, Julie Kewanyama, Karmjit Singh, Nirmal Singh, Nageshwara Gullapalli and Eric Osgard |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Mohit Rishi, MD, Academic Research, Department of Internal Medicine, University of Nevada, Reno School of Medicine, Renown Regional Medical Center, 1155 Mill St. W11, Reno, NV 89512, United States. mrishi@unr.edu |
| Key Words |
Simethicone; Intraluminal bubbles; Colonoscopy; Adenoma detection |
| Core Tip |
We conducted a randomized, controlled, prospective study to analyze the efficacy of oral simethicone addition to 2-liter polyethylene glycol bowel preparation for mucosal visibility improvement during colonoscopy. Significant reduction of bubbles/foam, improvement in total polyp detection, and total adenoma detection was seen with simethicone addition. Oral simethicone prior to colonoscopy helps clear intraluminal bubbles and alleviates the need to use intraprocedural simethicone flushes as recently advised by endoscope manufacturers. |
| Citation |
Rishi M, Kaur J, Ulanja M, Manasewitsch N, Svendsen M, Abdalla A, Vemala S, Kewanyama J, Singh K, Singh N, Gullapalli N, Osgard E. Randomized, double-blinded, placebo-controlled trial evaluating simethicone pretreatment with bowel preparation during colonoscopy. World J Gastrointest Endosc 2019; 11(6): 413-423 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
