Publication Name	World Journal of Gastroenterology
Manuscript ID	48303
Country of Manuscript Source	China

Specialty	Gastroenterology and Hepatology
Manuscript type	Meta-Analysis
Article Title	Is total laparoscopic pancreaticoduodenectomy superior to the open procedure? A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Hua Zhang, Xiang Lan, Bing Peng and Bo Li
Funding Agency and Grant Number
Correspondence To	Bo Li, MD, PhD, Professor, Surgeon, Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, 37 Guoxue Road, Wuhou District, Chengdu 610041, Sichuan Province, China. libohuaxi@163.com
Keywords	Total laparoscopic pancreaticoduodenectomy; Open pancreaticoduodenectomy; Safety; Feasibility; Meta-analysis;
Core Tip	This is a meta-analysis with the largest number of cases so far comparing total laparoscopic pancreaticoduodenectomy (TLPD) and open pancreaticoduodenectomy (OPD). In recent years, the reports or comparisions between TLPD and OPD are increasing, but most of them are with very small amount, the quality and the reliability are limited. In this meta-analysis, we reviewed the published literatures on this topic until now with the largest amount of cases, thus the conclusion is much more reliable. In addition, our study not only analysis the effects of laparoscopic skills in intraoperative parameters and postoperative complications, but also in oncological outcomes to ensure its safety and feasibility.
Citation	Zhang H, Lan X, Peng B, Li B. Is total laparoscopic pancreaticoduodenectomy superior to the open procedure? A meta-analysis. World J Gastroenterol 2019; In press

Received	2019-04-15 01:04
Peer-Review Started	2019-04-15 06:29
To Make the First Decision	2019-06-17 00:41
Return for Revision	2019-06-21 01:17
Revised	2019-07-10 06:35
Second Decision	2019-08-02 10:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-07 09:40
Articles in Press	2019-08-07 09:40
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-08-14 04:05
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Assistant Editor	Xiang Li
Science Editor	Jia-Ping Yan
Reviewer Code	03477516, 02484487, 00077376, 00505584, and 01221925
Editorial Director	Ze-Mao Gong
Journal Chief Editor
Company Chief Editor	Lian-Sheng Ma
Language Editor	Tian-Qi Wang
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director	Jin-Lei Wang
Proofing Editor-in-Chief	Lian-Sheng Ma

Manuscript File	48303-Review_Edited.docx
Answering Reviewers	48303-Answering reviewers.pdf
Audio Core Tip	48303-Audio core tip.mp3
Biostatistics Review Certificate	48303-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	48303-Conflict-of-interest statement.pdf
Copyright License Agreement	48303-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	48303-Language certificate.pdf
Supplementary Material	48303-Supplementary material.pdf
Peer-review Report	48303-Peer-review(s).pdf
Scientific Misconduct Check	48303-Scientific misconduct check.pdf
Scientific Editor Work List	48303-Scientific editor work list.pdf